LRP1B Antikörper (AA 3704-4547)

Produktnummer ABIN7601521

Produktdetails anti-LRP1B Antikörper

Target: LRP1B (Low Density Lipoprotein Receptor-Related Protein 1B (LRP1B))

Bindungsspezifität: AA 3704-4547

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRP1B Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA

Verwendungszweck: Anti-LRP1B Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-LRP1B Antibody Picoband® (ABIN7601521). Tested in ELISA, IHC applications. This antibody reacts with Human, Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human LRP1B recombinant protein (Position: D3704-K4547).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Liu, C.-X., Li, Y., Obermoeller-McCormick, L. M., Schwartz, A. L., Bu, G. The putative tumor suppressor LRP1B, a novel member of the low absorbance lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties with the LDL receptor-related protein. J. Biol. Chem. 276: 28889-28896, 2001. 2. Liu, C.-X., Musco, S., Lisitsina, N. M., Forgacs, E., Minna, J. D., Lisitsyn, N. A. LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines. Cancer Res. 60: 1961-1967, 2000. 3. Liu, C.-X., Musco, S., Lisitsina, N. M., Yaklichkin, S. Y., Lisitsyn, N. A. Genomic organization of a new candidate tumor suppressor gene, LRP1B. Genomics 69: 271-274, 2000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu LRP1B

Target: LRP1B (Low Density Lipoprotein Receptor-Related Protein 1B (LRP1B))

Andere Bezeichnung: LRP1B (LRP1B Produkte)

Hintergrund:

Synonyms: BAG family molecular chaperone regulator 5,BAG-5,Bcl-2-associated athanogene 5,BAG5,KIAA0873,

Tissue Specificity: Expressed in all tissues examined with lower levels in brain and testis.

Background: Low-density lipoprotein receptor-related protein 1B is a protein that in humans is encoded by the LRP1B gene. This gene encodes a member of the low density lipoprotein (LDL) receptor family. These receptors play a wide variety of roles in normal cell function and development due to their interactions with multiple ligands. Disruption of this gene has been reported in several types of cancer.

Molekulargewicht: 92 kDa

Gen-ID: 53353