UBA5 Antikörper (AA 37-389)

Produktnummer ABIN7601503

Der Kaninchen Polyklonal Anti-UBA5 Antikörper wurde für WB, ELISA, IHC und FACS validiert. Er ist geeignet, UBA5 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für UBA5 Antikörper (AA 37-389) (ABIN7601503)

Target: UBA5 (Ubiquitin-Like Modifier Activating Enzyme 5 (UBA5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-UBA5 Antikörper

Bindungsspezifität: AA 37-389

Verwendungszweck: Anti-UBA5 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-UBA5 Antibody Picoband® (ABIN7601503). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human UBA5 recombinant protein (Position: R37-D389).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Colin, E., Daniel, J., Ziegler, A., Wakim, J., Scrivo, A., Haack, T. B., Khiati, S., Denomme, A.-S., Amati-Bonneau, P., Charif, M., Procaccio, V., Reynier, P., and 19 others. Biallelic variants in UBA5 reveal that disruption of the UFM1 cascade can result in early-onset encephalopathy. Am. J. Hum. Genet. 99: 695-703, 2016. 2. Dou, T., Gu, S., Liu, J., Chen, F., Zeng, L., Guo, L., Xie, Y., Mao, Y. Isolation and characterization of ubiquitin-activating enzyme E1-domain containing 1, UBE1DC1. Molec. Biol. Rep. 32: 265-271, 2005. 3. Duan, R., Shi, Y., Yu, L., Zhang, G., Li, J., Lin, Y., Guo, J., Wang, J., Shen, L., Jiang, H., Wang, G., Tang, B. UBA5 mutations cause a new form of autosomal recessive cerebellar ataxia. PLoS One 11: e0149039, 2016. Note: Electronic Article.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu UBA5

Target: UBA5 (Ubiquitin-Like Modifier Activating Enzyme 5 (UBA5))

Andere Bezeichnung: UBA5

Hintergrund:

Synonyms: Rho-related GTP-binding protein Rho6,Rho family GTPase 1,Rnd1,RND1,RHO6,

Tissue Specificity: Mostly expressed in brain and liver.

Background: Ubiquitin-like modifier-activating enzyme 5 is a protein that in humans is encoded by the UBA5 gene. This gene encodes a member of the E1-like ubiquitin-activating enzyme family. This protein activates ubiquitin-fold modifier 1, a ubiquitin-like post-translational modifier protein, via the formation of a high-energy thioester bond. Alternative splicing results in multiple transcript variants. A pseudogene of this gene has been identified on chromosome 1.

Molekulargewicht: 50 kDa

Gen-ID: 79876