KLF10/TIEG1 Antikörper (AA 36-471)

Produktnummer ABIN7601477

Dieses Anti-KLF10/TIEG1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KLF10/TIEG1 in WB, ELISA, ICC und IF. Geeignet für Human.

Kurzübersicht für KLF10/TIEG1 Antikörper (AA 36-471) (ABIN7601477)

Target: KLF10/TIEG1 (KLF10) (Kruppel-Like Factor 10 (KLF10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLF10/TIEG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-KLF10/TIEG1 Antikörper

Bindungsspezifität: AA 36-471

Verwendungszweck: Anti-KLF10 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-KLF10 Antibody Picoband® (ABIN7601477). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human KLF10 recombinant protein (Position: K36-A471).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Blok, L. J., Grossmann, M. E., Perry, J. E., Tindall, D. J. Characterization of an early growth response gene which encodes a zinc finger transcription factor potentially involved in cell cycle regulation. Molec. Endocr. 9: 1610-1620, 1995. 2. Fautsch, M. P., Vrabel, A., Rickard, D., Subramaniam, M., Spelsberg, T. C., Wieben, E. D. Characterization of the mouse TGF-beta-inducible early gene (TIEG): conservation of exon and transcriptional regulatory sequences with evidence of additional transcripts. Mammalian Genome 9: 838-842, 1998. 3. Fautsch, M. P., Vrabel, A., Subramaniam, M., Hefferen, T. E., Spelsberg, T. C., Wieben, E. D. TGF-beta-inducible early gene (TIEG) also codes for early growth response alpha (EGR-alpha): evidence of multiple transcripts from alternate promoters. Genomics 51: 408-416, 1998.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu KLF10/TIEG1

Target: KLF10/TIEG1 (KLF10) (Kruppel-Like Factor 10 (KLF10))

Andere Bezeichnung: KLF10

Hintergrund:

Synonyms: Vacuolar protein sorting-associated protein 4B, Cell migration-inducing gene 1 protein, Suppressor of K (+) transport growth defect 1, Protein SKD1, VPS4B, SKD1, VPS42, MIG1

Tissue Specificity: Ubiquitously expressed.

Background: Krueppel-like factor 10 is a protein that in humans is encoded by the KLF10 gene. This gene encodes a member of a family of proteins that feature C2H2-type zinc finger domains. The encoded protein is a transcriptional repressor that acts as an effector of transforming growth factor beta signaling. Activity of this protein may inhibit the growth of cancers, particularly pancreatic cancer. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 55 kDa

Gen-ID: 7071

UniProt: Q13118

Pathways: Stem Cell Maintenance