NMS Antikörper (AA 36-144)

Produktnummer ABIN7601460

Produktdetails anti-NMS Antikörper

Target: NMS (Neuromedin S (NMS))

Bindungsspezifität: AA 36-144

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMS Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Verwendungszweck: Anti-Nms Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Nms Antibody Picoband® (ABIN7601460). Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Nms recombinant protein (Position: D36-N144).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Miyazato, M., Mori, K., Ida, T., Kojima, M., Murakami, N., Kangawa, K. Identification and functional analysis of a novel ligand for G protein-coupled receptor, neuromedin S. Regul. Pept. 145: 37-41, 2008. 2. Mori, K., Miyazato, M., Ida, T., Murakami, N., Serino, R., Ueta, Y., Kojima, M., Kangawa, K. Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. EMBO J. 24: 325-335, 2005. 3. Sakamoto, T., Nakahara, K., Maruyama, K., Katayama, T., Mori, K., Miyazato, M., Kangawa, K., Murakami, N. Neuromedin S regulates cardiovascular function through the sympathetic nervous system in mice. Peptides 32: 1020-1026, 2011.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu NMS

Target: NMS (Neuromedin S (NMS))

Andere Bezeichnung: Nms (NMS Produkte)

Hintergrund:

Synonyms: Transmembrane protein 240,TMEM240,C1orf70,

Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Background: Neuromedin S is a 36-amino acid neuropeptide found in the brain of humans and other mammals. This gene encodes a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in the regulation of circadian rhythm, anorexigenic action, antidiuretic action, cardiovascular function and stimulation of oxytocin and vasopressin release. Mice lacking the encoded neuropeptide exhibit decreased heart rate without any accompanying changes in blood pressure. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate the mature peptide.

Molekulargewicht: 150 kDa

Gen-ID: 433292

UniProt: Q5H8A1