SMC2 Antikörper (AA 359-1071)

Produktnummer ABIN7601453

Dieses Anti-SMC2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SMC2 in WB, ELISA, ICC, IF und FACS. Geeignet für Human, Ratte und Maus.

Kurzübersicht für SMC2 Antikörper (AA 359-1071) (ABIN7601453)

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMC2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Produktdetails anti-SMC2 Antikörper

Bindungsspezifität: AA 359-1071

Verwendungszweck: Anti-SMC2 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SMC2 Antibody Picoband® (ABIN7601453). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SMC2 recombinant protein (Position: L359-K1071).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 2/11/2014. 2. Schmiesing, J. A., Ball, A. R., Jr., Gregson, H. C., Alderton, J. M., Zhou, S., Yokomori, K. Identification of two distinct human SMC protein complexes involved in mitotic chromosome dynamics. Proc. Nat. Acad. Sci. 95: 12906-12911, 1998. 3. Schmiesing, J. A., Gregson, H. C., Zhou, S., Yokomori, K. A human condensin complex containing hCAP-C-hCAP-E and CNAP1, a homolog of Xenopus XCAP-D2, colocalizes with phosphorylated histone H3 during the early stage of mitotic chromosome condensation. Molec. Cell. Biol. 20: 6996-7006, 2000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu SMC2

Target: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Andere Bezeichnung: SMC2

Hintergrund:

Synonyms: Mediator of RNA polymerase II transcription subunit 14, Activator-recruited cofactor 150 kDa component, ARC150, Cofactor required for Sp1 transcriptional activation subunit 2, CRSP complex subunit 2, Mediator complex subunit 14, RGR1 homolog, hRGR1, Thyroid hormone receptor-associated protein complex 170 kDa component, Trap170, Transcriptional coactivator CRSP150, Vitamin D3 receptor-interacting protein complex 150 kDa component, DRIP150, MED14, ARC150, CRSP2, CXorf4, DRIP150, EXLM1, RGR1, TRAP170,

Tissue Specificity: Ubiquitous.

Background: Structural maintenance of chromosomes protein 2 (SMC-2) also known as chromosome-associated protein E (CAP-E) is a protein that in humans is encoded by the SMC2 gene. Predicted to enable ATP binding activity, chromatin binding activity, and single-stranded DNA binding activity. Involved in mitotic chromosome condensation. Located in condensed chromosome, cytoplasm, and nuclear lumen. Part of condensin complex.

Molekulargewicht: 136 kDa

Gen-ID: 10592

UniProt: O95347