OAS2 Antikörper (AA 35-742)

Produktnummer ABIN7601436

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch OAS2 in WB, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Maus und Ratte.

Kurzübersicht für OAS2 Antikörper (AA 35-742) (ABIN7601436)

Target: OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser OAS2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-OAS2 Antikörper

Bindungsspezifität: AA 35-742

Verwendungszweck: Anti-OAS2 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-OAS2 Antibody Picoband® (ABIN7601436). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse OAS2 recombinant protein (Position: H35-K742). Mouse OAS2 shares 62.4% and 77.5% amino acid (aa) sequence identity with human and rat ATF5, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse
ELISA, 0.1-0.5 μg/mL, Mouse
1. Hovanessian, A. G., Laurent, A. G., Chebath, J., Galabru, J., Robert, N., Svab, J. Identification of 69-kd and 100-kd forms of 2-5A synthetase in interferon-treated human cells by specific monoclonal antibodies. EMBO J. 6: 1273-1280, 1987. 2. Hovnanian, A., Rebouillat, D., Mattei, M.-G., Levy, E. R., Marie, I., Monaco, A. P., Hovanessian, A. G. The human 2-prime,5-prime-oligoadenylate synthetase locus is composed of three distinct genes clustered on chromosome 12q24.2 encoding the 100-, 69-, and 40- kDa forms. Genomics 52: 267-277, 1998. 3. Marie, I., Galabru, J., Svab, J., Hovanessian, A. G. Preparation and characterization of polyclonal antibodies specific for the 69 and 100 k-dalton forms of human 2-5A synthetase. Biochem. Biophys. Res. Commun. 160: 580-587, 1989.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu OAS2

Target: OAS2 (2'-5'-Oligoadenylate Synthetase 2, 69/71kDa (OAS2))

Andere Bezeichnung: OAS2

Hintergrund:

Synonyms: Oas2, oasl11, 2'-5'-oligoadenylate synthase 2, (2-5'oligo(A synthase 2, 2-5A synthase 2, EC 2.7.7.84, 2',5'-oligoadenylate synthetase-like 11

Background: 2'-5'-oligoadenylate synthetase 2 is an enzyme that in humans is encoded by the OAS2 gene. Enables 2'-5'-oligoadenylate synthetase activity and double-stranded RNA binding activity. Involved in defense response to virus, regulation of lactation, and type I interferon signaling pathway. Acts upstream of or within RNA catabolic process, interleukin-27-mediated signaling pathway, and response to bacterium. Predicted to be located in perinuclear region of cytoplasm. Predicted to be active in cytosol, membrane, and nucleoplasm. Is expressed in embryo. Orthologous to human OAS2 (2'-5'-oligoadenylate synthetase 2).

Molekulargewicht: 69 kDa

Gen-ID: 246728

UniProt: E9Q9A9

Pathways: Hepatitis C