RS1 Antikörper (AA 34-224)

Produktnummer ABIN7601377

Produktdetails anti-RS1 Antikörper

Target: RS1 (Retinoschisin 1 (RS1))

Bindungsspezifität: AA 34-224

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RS1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Verwendungszweck: Anti-RS1 Antibody Picoband®

Produktmerkmale: Anti-RS1 Antibody Picoband® (ABIN7601377). Tested in WB, ELISA applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RS1 recombinant protein (Position: Y34-A224). Human RS1 shares 96.9% amino acid (aa) sequence identity with mouse RS1.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Byrne, J., Warburton, D. Male excess among anatomically normal fetuses in spontaneous abortions. Am. J. Med. Genet. 26: 605-611, 1987. 2. Eriksson, A. W., Vainio-Mattila, B., Krause, U., Fellman, J., Forsius, H. Secondary sex ratio in families with X-chromosomal disorders. Hereditas 57: 373-381, 1967. 3. Gehrig, A., Weber, B. H. F., Lorenz, B., Andrassi, M. First molecular evidence for a de novo mutation in RS1 (XLRS1) associated with X-linked juvenile retinoschisis. J. Med. Genet. 36: 932-934, 1999.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu RS1

Target: RS1 (Retinoschisin 1 (RS1))

Andere Bezeichnung: RS1 (RS1 Produkte)

Hintergrund: Retinoschisin also known as X-linked juvenile retinoschisis protein is a lectin that in humans is encoded by the RS1 gene. This gene encodes an extracellular protein that plays a crucial role in the cellular organization of the retina. The encoded protein is assembled and secreted from photoreceptors and bipolar cells as a homo-oligomeric protein complex. Mutations in this gene are responsible for X-linked retinoschisis, a common, early-onset macular degeneration in males that results in a splitting of the inner layers of the retina and severe loss in vision.

Molekulargewicht: 25 kDa

Gen-ID: 6247

UniProt: O15537