FAM111B Antikörper (AA 328-726)

Produktnummer ABIN7601335

Der Kaninchen Polyklonal anti-FAM111B Antikörper wird verwendet zum Nachweis von FAM111B in Proben von Human. Er wurde validiert für ELISA, IHC, WB und FACS.

Kurzübersicht für FAM111B Antikörper (AA 328-726) (ABIN7601335)

Target: FAM111B (Family with Sequence Similarity 111, Member B (FAM111B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM111B Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-FAM111B Antikörper

Bindungsspezifität: AA 328-726

Verwendungszweck: Anti-FAM111B Antibody

Homologie: Human FAM111B shares 45.4% amino acid (aa) sequence identity with mouse FAM111B.

Produktmerkmale: Anti-FAM111B Antibody. Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human FAM111B recombinant protein (Position: Q328-D726). Human FAM111B shares 45.4% amino acid (aa) sequence identity with mouse FAM111B.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu FAM111B

Target: FAM111B (Family with Sequence Similarity 111, Member B (FAM111B))

Andere Bezeichnung: FAM111B

Hintergrund:

Background: This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐,like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1.

Gene Full Name: FAM111 trypsin like peptidase B

Molekulargewicht: 85 kDa

Gen-ID: 374393

UniProt: Q6SJ93