Der Kaninchen Polyklonal Anti-FAM111B Antikörper wurde für ELISA, IHC, WB und FACS validiert. Er ist geeignet, FAM111B in Proben von Human zu detektieren.
Produktnummer ABIN7601335
Kurzübersicht für FAM111B Antikörper (AA 328-726) (ABIN7601335)
Target
FAM111B
(Family with Sequence Similarity 111, Member B (FAM111B))
Reaktivität
Human
Wirt
Kaninchen
Klonalität
Polyklonal
Konjugat
Dieser FAM111B Antikörper ist unkonjugiert
Applikation
ELISA, Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS)
Bindungsspezifität
AA 328-726
Verwendungszweck
Anti-FAM111B Antibody
Produktmerkmale
Anti-FB Antibody (ABIN7601335). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
Aufreinigung
Immunogen affinity purified.
Immunogen
E.coli-derived human FAM111B recombinant protein (Position: Q328-D726). Human FAM111B shares 45.4% amino acid (aa) sequence identity with mouse FAM111B.
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Target
FAM111B
(Family with Sequence Similarity 111, Member B (FAM111B))
Andere Bezeichnung
FAM111B
Hintergrund
This gene encodes a protein with a trypsin-like cysteine/serine peptidase domain in the C-terminus. Mutations in this gene are associated with an autosomal dominant form of hereditary fibrosing poikiloderma (HFP). Affected individuals display mottled pigmentation, telangiectasia, epidermal atrophy, tendon contractures, and progressive pulmonary fibrosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. A paralog of this gene which also has a trypsin‐,like peptidase domain, FAM111A, is located only 16 kb from this gene on human chromosome 11q12.1.