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Tpp2 Antikörper (AA 32-1001)

Tpp2 Reaktivität: Human, Maus, Ratte WB, IF, IHC, ELISA, FACS, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7601293
  • Target Alle Tpp2 Antikörper anzeigen
    Tpp2 (Tripeptidyl Peptidase II (Tpp2))
    Bindungsspezifität
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 32-1001
    Reaktivität
    • 24
    • 15
    • 13
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 23
    • 1
    Kaninchen
    Klonalität
    • 22
    • 2
    Polyklonal
    Konjugat
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Tpp2 Antikörper ist unkonjugiert
    Applikation
    • 12
    • 8
    • 8
    • 7
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Verwendungszweck
    Anti-Tripeptidyl peptidase II/TPPII/TPP2 Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins.
    Produktmerkmale
    Anti-Tripeptidyl peptidase II/TPPII/TPP2 Antibody Picoband® (ABIN7601293). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human Tripeptidyl peptidase II/TPPII/TPP2 recombinant protein (Position: E32-K1001).
    Isotyp
    IgG
    Top Product
    Discover our top product Tpp2 Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Atallah, I., Quinodoz, M., Campos-Xavier, B., Peter, V. G., Fouriki, A., Bonvin, C., Bottani, A., Kumps, C., Angelini, F., Bellutti Enders, F., Christen-Zaech, S., Rizzi, M., and 11 others. Immune deficiency, autoimmune disease and intellectual disability: a pleiotropic disorder caused by biallelic variants in the TPP2 gene. Clin. Genet. 99: 780-788, 2021. 2. Balow, R.-M., Ragnarsson, U., Zetterqvist, O. Tripeptidyl aminopeptidase in the extralysosomal fraction of rat liver. J. Biol. Chem. 258: 11622-11628, 1983. 3. Bermingham, N. A., McKay, T., Hoyle, J., Hernandez, D., Martin, J. E., Fisher, E. M. C. The gene encoding tripeptidyl peptidase II maps to chromosome 1 in the mouse. Mammalian Genome 7: 390 only, 1996.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target
    Tpp2 (Tripeptidyl Peptidase II (Tpp2))
    Andere Bezeichnung
    TPP2 (Tpp2 Produkte)
    Hintergrund

    Synonyms: Ubiquitin carboxyl-terminal hydrolase 21, Deubiquitinating enzyme 21, Ubiquitin thioesterase 21, Ubiquitin-specific-processing protease 21, USP21, USP23, PP1490

    Tissue Specificity: Highly expressed in heart, pancreas and skeletal muscle. Also expressed in brain, placenta, liver and kidney, and at very low level in lung.

    Background: Tripeptidyl-peptidase 2 is an enzyme that in humans is encoded by the TPP2 gene. This gene encodes a mammalian peptidase that, at neutral pH , removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase, the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class.

    Molekulargewicht
    138 kDa
    Gen-ID
    7174
    UniProt
    P29144
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