GLRX3 Antikörper (AA 31-307)

Produktnummer ABIN7601262

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GLRX3 in WB, ELISA und FACS. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für GLRX3 Antikörper (AA 31-307) (ABIN7601262)

Target: GLRX3 (Glutaredoxin 3 (GLRX3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLRX3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-GLRX3 Antikörper

Bindungsspezifität: AA 31-307

Verwendungszweck: Anti-GLRX3 Antibody Picoband®

Produktmerkmale: Anti-GLRX3 Antibody Picoband® (ABIN7601262). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GLRX3 recombinant protein (Position: K31-V307). Human GLRX3 shares 94.6% and 94.9% amino acid (aa) sequence identity with mouse and rat GLRX3, respectively.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 4/22/2009. 2. Haunhorst, P., Hanschmann, E.-M., Brautigam, L., Stehling, O., Hoffmann, B., Muhlenhoff, U., Lill, R., Berndt, C., Lillig, C. H. Crucial function of vertebrate glutaredoxin 3 (PICOT) in iron homeostasis and hemoglobin maturation. Molec. Biol. Cell 24: 1895-1903, 2013. 3. Jeong, D., Kim, J. M., Cha, H., Oh, J. G., Park, J., Yun, S.-H., Ju, E.-S., Jeon, E.-S., Hajjar, R. J., Park, W. J. PICOT attenuates cardiac hypertrophy by disrupting calcineurin-NFAT signaling. Circ. Res. 102: 711-719, 2008.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu GLRX3

Target: GLRX3 (Glutaredoxin 3 (GLRX3))

Andere Bezeichnung: GLRX3

Hintergrund: Glutaredoxin-3 is a protein that in humans is encoded by the GLRX3 gene. This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene.

Molekulargewicht: 40 kDa

Gen-ID: 10539

UniProt: O76003

Pathways: Cell RedoxHomeostasis