Fibulin 1 Antikörper (AA 30-703)

Produktnummer ABIN7601231

Dieses Anti-Fibulin 1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Fibulin 1 in WB, ICC, ELISA, FACS und IF. Geeignet für Human.

Kurzübersicht für Fibulin 1 Antikörper (AA 30-703) (ABIN7601231)

Target: Fibulin 1 (FBLN1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Fibulin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunocytochemistry (ICC), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-Fibulin 1 Antikörper

Bindungsspezifität: AA 30-703

Verwendungszweck: Anti-Fibulin 1/FBLN1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-Fibulin 1/FBLN1 Antibody Picoband® (ABIN7601231). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Fibulin 1/FBLN1 recombinant protein (Position: D30-F703).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Argraves, W. S., Dickerson, K., Burgess, W. H., Ruoslahti, E. Fibulin, a novel protein that interacts with the fibronectin receptor-beta subunit cytoplasmic domain. Cell 58: 623-629, 1989. 2. Argraves, W. S., Tran, H., Burgess, W. H., Dickerson, K. Fibulin is an extracellular matrix and plasma glycoprotein with repeated domain structure. J. Cell Biol. 111: 3155-3164, 1990. 3. Bohlega, S., Al-Ajlan, H., Al-Saif, A. Mutation of fibulin-1 causes a novel syndrome involving the central nervous system and connective tissues. Europ. J. Hum. Genet. 22: 640-643, 2014.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu Fibulin 1

Target: Fibulin 1 (FBLN1)

Andere Bezeichnung: FBLN1

Hintergrund:

Synonyms: Insulin gene enhancer protein ISL-1,Islet-1,ISL1,

Tissue Specificity: Expressed in subsets of neurons of the adrenal medulla and dorsal root ganglion, inner nuclear and ganglion cell layers in the retina, the pineal and some regions of the brain.

Background: FBLN1 is the gene encoding fibulin-1, an extracellular matrix and plasma protein. Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants.

Molekulargewicht: 90 kDa

Gen-ID: 2192

UniProt: P23142