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TRAF7 Antikörper (AA 29-670)

Dieses Anti-TRAF7-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TRAF7 in ELISA, WB und FACS. Geeignet für Human.
Produktnummer ABIN7601144

Kurzübersicht für TRAF7 Antikörper (AA 29-670) (ABIN7601144)

Target

Alle TRAF7 Antikörper anzeigen
TRAF7 (TNF Receptor-Associated Factor 7 (TRAF7))

Reaktivität

  • 28
  • 13
  • 12
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 28
Kaninchen

Klonalität

  • 28
Polyklonal

Konjugat

  • 11
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
Dieser TRAF7 Antikörper ist unkonjugiert

Applikation

  • 10
  • 8
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
ELISA, Western Blotting (WB), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 29-670

    Verwendungszweck

    Anti-TRAF7 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-TRAF7 Antibody Picoband® (ABIN7601144). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human TRAF7 recombinant protein (Position: R29-C670).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.25 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Bouwmeester, T., Bauch, A., Ruffner, H., Angrand, P.-O., Bergamini, G., Croughton, K., Cruciat, C., Eberhard, D., Gagneur, J., Ghidelli, S., Hopf, C., Huhse, B., and 16 others. A physical and functional map of the human TNF-alpha/NF-kappa-B signal transduction pathway. Nature Cell Biol. 6: 97-105, 2004. Note: Erratum: Nature Cell Biol. 6: 465 only, 2004. 2. Krumm, N., Turner, T. N., Baker, C., Vives, L., Mohajeri, K., Witherspoon, K., Raja, A., Coe, B. P., Stessman, H. A., He, Z.-X., Leal, S. M., Bernier, R., Eichler, E. E. Excess of rare, inherited truncating mutations in autism. Nature Genet. 47: 582-588, 2015. 3. Tokita, M. J., Chen, C.-A., Chitayat, D., Macnamara, E., Rosenfeld, J. A., Hanchard, N., Lewis, A. M., Brown, C. W., Marom, R., Shao, Y., Novacic, D., Wolfe, L., and 25 others. De novo missense variants in TRAF7 cause developmental delay, congenital anomalies, and dysmorphic features. Am. J. Hum. Genet. 103: 154-162, 2018.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    TRAF7 (TNF Receptor-Associated Factor 7 (TRAF7))

    Andere Bezeichnung

    TRAF7

    Hintergrund

    Synonyms: Long-chain-fatty-acid--CoA ligase 3,6.2.1.3,Long-chain acyl-CoA synthetase 3,LACS 3,ACSL3,ACS3, FACL3, LACS3,

    Tissue Specificity: Expressed in breast, ductal and invasive ductal carcinomas of the breast, sporadic colorectal adenomas and carcinomas (at protein level). Expressed in fetal brain. Expressed in lung, amygdala, eye, prostate, pancreatic and prostate cancers, head and neck tumors and embryonal tumor.

    Background: Tumor necrosis factor (TNF, see MIM 191160) receptor-associated factors, such as TRAF7, are signal transducers for members of the TNF receptor superfamily (see MIM 191190). TRAFs are composed of an N-terminal cysteine/histidine-rich region containing zinc RING and/or zinc finger motifs, a coiled-coil (leucine zipper) motif, and a homologous region that defines the TRAF family, the TRAF domain, which is involved in self-association and receptor binding.

    Molekulargewicht

    75 kDa

    Gen-ID

    84231

    UniProt

    Q6Q0C0
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