TOE1 Antikörper (AA 28-501)

Produktnummer ABIN7601080

Der Kaninchen Polyklonal Anti-TOE1-Antikörper wurde für WB, ELISA, IF, ICC und FACS validiert. Er ist geeignet, TOE1 in Proben von Human zu detektieren.

Kurzübersicht für TOE1 Antikörper (AA 28-501) (ABIN7601080)

Target: TOE1 (Target of EGR1, Member 1 (Nuclear) (TOE1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TOE1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Produktdetails anti-TOE1 Antikörper

Bindungsspezifität: AA 28-501

Verwendungszweck: Anti-TOE1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-TOE1 Antibody Picoband® (ABIN7601080). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TOE1 recombinant protein (Position: E28-Q501).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.1-0.25 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Anderson, C., Davies, J. H., Lamont, L., Foulds, N. Early pontocerebellar hypoplasia with vanishing testes: a new syndrome? Am. J. Med. Genet. 155A: 667-672, 2011. 2. Brault, L. S., Cooper, C. A., Famula, T. R., Murray, J. D., Penedo, M. C. T. Mapping of equine cerebellar abiotrophy to ECA2 and identification of a potential causative mutation affecting expression of MUTYH. Genomics 97: 121-129, 2011. 3. de Belle, I., Wu, J.-X., Sperandio, S., Mercola, D., Adamson, E. D. In vivo cloning and characterization of a new growth suppressor protein TOE1 as a target gene of Egr1. J. Biol. Chem. 278: 14306-14312, 2003.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu TOE1

Target: TOE1 (Target of EGR1, Member 1 (Nuclear) (TOE1))

Andere Bezeichnung: TOE1

Hintergrund:

Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6

Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.

Background: Target of EGR1 protein 1 is a protein that in humans is encoded by the TOE1 gene. Enables poly(A)-specific ribonuclease activity and snRNA binding activity. Involved in RNA phosphodiester bond hydrolysis, exonucleolytic and snRNA 3'-end processing. Located in Cajal body and cytoplasm. Implicated in pontocerebellar hypoplasia type 7.

Molekulargewicht: 57 kDa

Gen-ID: 114034