PI16 Antikörper (AA 28-363)

Produktnummer ABIN7601074

Der Kaninchen Polyklonal Anti-PI16-Antikörper wurde für WB, IHC, ELISA und FACS validiert. Er ist geeignet, PI16 in Proben von Human, Maus, Affe und Ratte zu detektieren.

Kurzübersicht für PI16 Antikörper (AA 28-363) (ABIN7601074)

Target: PI16 (Peptidase Inhibitor 16 (PI16))

Reaktivität: Human, Maus, Affe, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PI16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Produktdetails anti-PI16 Antikörper

Bindungsspezifität: AA 28-363

Verwendungszweck: Anti-PI-16/PI16 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-PI-16/PI16 Antibody Picoband® (ABIN7601074). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PI-16/PI16 recombinant protein (Position: L28-L363).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human, Mouse
ELISA, 0.1-0.5 μg/mL, -
1. Eeles, R. A., Kote-Jarai, Z., Giles, G. G., Al Olama, A. A., Guy, M., Jugurnauth, S. K., Mulholland, S., Leongamornlert, D. A., Edwards, S. M., Morrison, J., Field, H. I., Southey, M. C., and 37 others. Multiple newly identified loci associated with prostate cancer susceptibility. Nature Genet. 40: 316-321, 2008. 2. Buckland, P. R., Hoogendoorn, B., Coleman, S. L., Guy, C. A., Smith, S. K., O'Donovan, M. C. Strong bias in the location of functional promoter polymorphisms. Hum. Mutat. 26: 214-223, 2005. 3. Lou, H., Yeager, M., Li, H., Bosquet, J. G., Hayes, R. B., Orr, N., Yu, K., Hutchinson, A., Jacobs, K. B., Kraft, P., Wacholder, S., Chatterjee, N., and 24 others. Fine mapping and functional analysis of a common variant in MSMB on chromosome 10q11.2 associated with prostate cancer susceptibility. Proc. Nat. Acad. Sci. 106: 7933-7938, 2009.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu PI16

Target: PI16 (Peptidase Inhibitor 16 (PI16))

Andere Bezeichnung: PI16

Hintergrund:

Synonyms: Interleukin-36 alpha, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon, Interleukin-1 family member 6, IL-1F6, IL36A, FIL1E, IL1E, IL1F6

Tissue Specificity: Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.

Background: Peptidase inhibitor 16 is a protein that in humans is encoded by the PI16 gene. PI16 (Peptidase Inhibitor 16) is a variable molecular weight (MW) member of the CRISP family of proteins. It is expressed by cardiomyocytes and serves as an autocrine negative growth regulator.

Molekulargewicht: 70-75 kDa

Gen-ID: 221476