NFRKB Antikörper (AA 270-994)

Produktnummer ABIN7601036

Produktdetails anti-NFRKB Antikörper

Target: NFRKB (Nuclear Factor Related To KappaB Binding Protein (NFRKB))

Bindungsspezifität: AA 270-994

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFRKB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Verwendungszweck: Anti-NFRKB Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-NFRKB Antibody Picoband® (ABIN7601036). Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human NFRKB recombinant protein (Position: H270-L994).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Adams, B. S., Leung, K., Meltzer, P. S., Lewis, K. A., Wagner-McPherson, C., Evans, G. A., Nabel, G. J. Localization of the gene encoding R-kappa-B (NFRKB), a tissue-specific DNA binding protein, to chromosome 11q24-q25. Genomics 14: 270-274, 1992.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu NFRKB

Target: NFRKB (Nuclear Factor Related To KappaB Binding Protein (NFRKB))

Andere Bezeichnung: NFRKB (NFRKB Produkte)

Hintergrund:

Synonyms: Angiomotin-like protein 2, Leman coiled-coil protein, LCCP, AMOTL2, KIAA0989

Background: NFRKB (nuclear factor related to kappa-B-binding protein) was first identified as a factor that could bind a variant NF-kappa B site in the interleukin-2 receptor alpha (IL-2R alpha) gene. NFRKB appears to be a transcription factor central to immune cell development. Evidence of this comes from the identification of NFRKB as an amplified gene in several cases of acute myeloid leukemia. Additionally, in another clinical case, a partial deletion of the chromosomal region that includes NFRKB is shown to be associated with combined cellular immunodeficiency.

Molekulargewicht: 175 kDa

Gen-ID: 4798

UniProt: Q6P4R8