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IFI30 Antikörper (AA 27-250)

Der Kaninchen Polyklonal Anti-IFI30-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, IFI30 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN7601002

Kurzübersicht für IFI30 Antikörper (AA 27-250) (ABIN7601002)

Target

Alle IFI30 Antikörper anzeigen
IFI30 (Interferon, gamma-Inducible Protein 30 (IFI30))

Reaktivität

  • 31
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte

Wirt

  • 27
  • 5
  • 1
Kaninchen

Klonalität

  • 30
  • 3
Polyklonal

Konjugat

  • 19
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser IFI30 Antikörper ist unkonjugiert

Applikation

  • 16
  • 13
  • 13
  • 7
  • 6
  • 4
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 15
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 27-250

    Verwendungszweck

    Anti-IFI30 Antibody Picoband®

    Produktmerkmale

    Anti-IFI30 Antibody Picoband® (ABIN7601002). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human IFI30 recombinant protein (Position: S27-K250). Human IFI30 shares 66.3% and 68.8% amino acid (aa) sequence identity with mouse and rat IFI30, respectively.
  • Applikationshinweise

    Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Arunachalam, B., Phan, U. T., Geuze, H. J., Cresswell, P. Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon-inducible lysosomal thiol reductase (GILT). Proc. Nat. Acad. Sci. 97: 745-750, 2000. 2. Maric, M., Arunachalam, B., Phan, U. T., Dong, C., Garrett, W. S., Cannon, K. S., Alfonso, C., Karlsson, L., Flavell, R. A., Cressell, P. Defective antigen processing in GILT-free mice. Science 294: 1361-1365, 2001. 3. Phan, U. T., Arunachalam, B., Cresswell, P. Gamma-interferon-inducible lysosomal thiol reductase (GILT): maturation, activity, and mechanism of action. J. Biol. Chem. 275: 25907-25914, 2000.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    IFI30 (Interferon, gamma-Inducible Protein 30 (IFI30))

    Andere Bezeichnung

    IFI30

    Hintergrund

    Gamma-interferon-inducible lysosomal thiol reductase is an enzyme that, in humans, is encoded by the IFI30 gene. The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing.

    Molekulargewicht

    23 kDa

    Gen-ID

    10437

    UniProt

    P13284
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