ADAM28 Antikörper (AA 26-195)

Produktnummer ABIN7600945

Der Kaninchen Polyklonal Anti-ADAM28-Antikörper wurde für WB, IHC, ELISA und FACS validiert. Er ist geeignet, ADAM28 in Proben von Maus und Ratte zu detektieren.

Kurzübersicht für ADAM28 Antikörper (AA 26-195) (ABIN7600945)

Target: ADAM28 (ADAM Metallopeptidase Domain 28 (ADAM28))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAM28 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Produktdetails anti-ADAM28 Antikörper

Bindungsspezifität: AA 26-195

Verwendungszweck: Anti-Adam28 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Adam28 Antibody Picoband® (ABIN7600945). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived rat Adam28 recombinant protein (Position: K26-K195).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Mouse
ELISA, 0.1-0.5 μg/mL,
1. Bates, E. E. M., Fridman, W. H., Mueller, C. G. F. The ADAMDEC1 (decysin) gene structure: evolution by duplication in a metalloprotease gene cluster on chromosome 8p12. Immunogenetics 54: 96-105, 2002. 2. Bridges, L. C., Tani, P. H., Hanson, K. R., Roberts, C. M., Judkins, M. B., Bowditch, R. D. The lymphocyte metalloprotease MDC-L (ADAM28) is a ligand for the integrin alpha-4/beta-1. J. Biol. Chem. 277: 3784-3792, 2002. 3. Jury, J. A., Perry, A. C. F., Hall, L. Identification, sequence analysis and expression of transcripts encoding a putative metalloproteinase, eMDC II, in human and macaque epididymis. Molec. Hum. Reprod. 5: 1127-1134, 1999.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu ADAM28

Target: ADAM28 (ADAM Metallopeptidase Domain 28 (ADAM28))

Andere Bezeichnung: ADAM28

Hintergrund:

Synonyms: Disintegrin and metalloproteinase domain-containing protein 28,ADAM 28,3.4.24.-,Epididymal metalloproteinase-like, disintegrin-like, and cysteine-rich protein II,eMDC II,Metalloproteinase-like, disintegrin-like, and cysteine-rich protein L,MDC-L,ADAM28,ADAM23, MDCL,

Tissue Specificity: Expressed predominantly in secondary lymphoid tissues, such as lymph node, spleen, small intestine, stomach, colon, appendix and trachea. The lymphocyte population is responsible for expression of this protein in these tissues. Isoform 2 is expressed preferentially in spleen.

Background: Disintegrin and metalloproteinase domain-containing protein 28 is an enzyme that in humans is encoded by the ADAM28 gene. This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a lymphocyte-expressed ADAM protein. And this gene is present in a gene cluster with other members of the ADAM family on chromosome 8. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 87 kDa

Gen-ID: 290344