TMEM129 Antikörper (AA 25-362)
Kurzübersicht für TMEM129 Antikörper (AA 25-362) (ABIN7600907)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 25-362
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Verwendungszweck
- Anti-TMEM129 Antibody Picoband®
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Produktmerkmale
- Anti-TM Antibody Picoband® (ABIN7600907). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human TMEM129 recombinant protein (Position: E25-R362).
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Isotyp
- IgG
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Applikationshinweise
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Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 9/2/2014. 2. van den Boomen, D. J. H., Timms, R. T., Grice, G. L., Stagg, H. R., Skodt, K., Dougan, G., Nathan, J. A., Lehner, P. J. TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I. Proc. Nat. Acad. Sci. 111: 11425-11430, 2014. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- TMEM129 (Transmembrane Protein 129 (TMEM129))
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Andere Bezeichnung
- TMEM129
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Hintergrund
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Synonyms: Protein eva-1 homolog A, Protein FAM176A, Transmembrane protein 166, EVA1A, FAM176A, TMEM166, SP24
Tissue Specificity: Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.
Background: Enables ubiquitin protein ligase activity. Involved in protein polyubiquitination, retrograde protein transport, ER to cytosol, and ubiquitin-dependent ERAD pathway. Located in endoplasmic reticulum.
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Molekulargewicht
- 50 kDa
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Gen-ID
- 92305
Target
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