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CCL8 Antikörper (AA 24-99)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CCL8 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7600863

Kurzübersicht für CCL8 Antikörper (AA 24-99) (ABIN7600863)

Target

Alle CCL8 Antikörper anzeigen
CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

Reaktivität

  • 48
  • 13
  • 5
  • 4
  • 2
  • 2
  • 2
Human, Maus, Ratte

Wirt

  • 56
  • 16
  • 1
  • 1
Kaninchen

Klonalität

  • 57
  • 17
Polyklonal

Konjugat

  • 43
  • 8
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CCL8 Antikörper ist unkonjugiert

Applikation

  • 46
  • 24
  • 24
  • 19
  • 16
  • 14
  • 14
  • 6
  • 5
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 22
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-99

    Verwendungszweck

    Anti-MCP2/CCL8 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-MCP2/CCL8 Antibody Picoband® (ABIN7600863). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human MCP2/CCL8 recombinant protein (Position: Q24-P99).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Van Coillie, E., Fiten, P., Nomiyama, H., Sakaki, Y., Miura, R., Yoshie, O., Van Damme, J., Opdenakker, G. The human MCP-2 gene (SCYA8): cloning, sequence analysis, tissue expression, and assignment to the CC chemokine gene contig on chromosome 17q11.2. Genomics 40: 323-331, 1997. 2. Van Damme, J., Proost, P., Lenaerts, J.-P., Opdenakker, G. Structural and functional identification of two human, tumor-derived monocyte chemotactic proteins (MCP-2 and MCP-3) belonging to the chemokine family. J. Exp. Med. 176: 59-65, 1992.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

    Andere Bezeichnung

    CCL8

    Hintergrund

    Synonyms: C-C motif chemokine 8, Monocyte chemoattractant protein 2, Monocyte chemotactic protein 2, MCP-2, Small-inducible cytokine A8, Ccl8, Mcp2, Scya8

    Background: Chemokine (C-C motif) ligand 8 (CCL8), also known as monocyte chemoattractant protein 2 (MCP2), is a protein that in humans is encoded by the CCL8 gene. This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.

    Molekulargewicht

    22 kDa

    Gen-ID

    6355

    UniProt

    P80075
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