DCT Antikörper (AA 24-519)

Produktnummer ABIN7600843

Der Kaninchen Polyklonal Anti-DCT-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, DCT in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für DCT Antikörper (AA 24-519) (ABIN7600843)

Target: DCT (Dopachrome Tautomerase (DCT))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-DCT Antikörper

Bindungsspezifität: AA 24-519

Verwendungszweck: Anti-TRP2/DCT Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-TRP2/DCT Antibody Picoband® (ABIN7600843). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TRP2/DCT recombinant protein (Position: Q24-A519).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Bouchard, B., Del Marmol, V., Jackson, I. J., Cherif, D., Dubertret, L. Molecular characterization of a human tyrosinase-related-protein-2 cDNA: patterns of expression in melanocytic cells. Europ. J. Biochem. 219: 127-134, 1994. 2. Budd, P. S., Jackson, I. J. Structure of the mouse tyrosinase-related protein-2/dopachrome tautomerase (Tyrp2/Dct) gene and sequence of two novel slaty alleles. Genomics 29: 35-43, 1995. 3. Cassady, J. L., Sturm, R. A. Sequence of the human dopachrome tautomerase-encoding TRP-2 cDNA. Gene 143: 295-298, 1994.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu DCT

Target: DCT (Dopachrome Tautomerase (DCT))

Andere Bezeichnung: DCT

Hintergrund:

Synonyms: Beta-galactosidase, Glb1, Glb1_mapped, rCG_25043

Background: Dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2), also known as DCT, is a human gene. The TYR-related proteins, TRP1 and TRP2, are also specifically expressed in melanocytes, and they likewise contribute to the synthesis of melanin within the melanosomes. The TRPs, including TYR, all share a similar transmembrane region, contain two metal-binding regions and a cysteinerich epidermal growth factor motif, and are localized in the melanosomal membrane. These proteins, however, have distinct catalytic activity, and they individually contribute to the biosynthesis of melanin biopolymers. The TRPs are believed to exist as a multi-enzyme complex, as these proteins form aggregates together, and the expression of TRP1 also helps stabilize TYR in melanocytes.

Molekulargewicht: 59 kDa

Gen-ID: 1638

UniProt: P40126