TSPYL5 Antikörper (AA 24-337)

Produktnummer ABIN7600825

Der Kaninchen Polyklonal Anti-TSPYL5-Antikörper wurde für WB, FACS und ELISA validiert. Er ist geeignet, TSPYL5 in Proben von Human zu detektieren.

Kurzübersicht für TSPYL5 Antikörper (AA 24-337) (ABIN7600825)

Target: TSPYL5 (TSPY-Like 5 (TSPYL5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TSPYL5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Produktdetails anti-TSPYL5 Antikörper

Bindungsspezifität: AA 24-337

Verwendungszweck: Anti-TSPYL5 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-TSPYL5 Antibody Picoband® (ABIN7600825). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human TSPYL5 recombinant protein (Position: R24-Q337).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Epping, M. T., Meijer, L. A. T., Krijgsman, O., Bos, J. L., Pandolfi, P. P., Bernards, R. TSPYL5 suppresses p53 levels and function by physical interaction with USP7. Nature Cell Biol. 13: 102-108, 2011. 2. Jung, Y., Park, J., Bang, Y.-J., Kim, T.-Y. Gene silencing of TSPYL5 mediated by aberrant promoter methylation in gastric cancers. Lab. Invest. 88: 153-160, 2008. 3. Kim, E. J., Lee, S. Y., Kim, T. R., Choi, S. I., Cho, E. W., Kim, K. C., Kim, I. G. TSPYL5 is involved in cell growth and the resistance to radiation in A549 cells via the regulation of p21(WAF1/Cip1) and PTEN/AKT pathway. Biochem. Biophys. Res. Commun. 392: 448-453, 2010.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu TSPYL5

Target: TSPYL5 (TSPY-Like 5 (TSPYL5))

Andere Bezeichnung: TSPYL5

Hintergrund:

Synonyms: RNA-binding protein Nova-2, Astrocytic NOVA1-like RNA-binding protein, Neuro-oncological ventral antigen 2, NOVA2, ANOVA, NOVA3

Tissue Specificity: Brain. Expression restricted to astrocytes.

Background: TSPY like 5 is a protein that in humans is encoded by the TSPYL5 gene. Predicted to enable chromatin binding activity and histone binding activity. Involved in several processes, including cellular response to gamma radiation, positive regulation of protein kinase B signaling, and positive regulation of protein ubiquitination. Predicted to be active in chromatin and nucleus.

Molekulargewicht: 48 kDa

Gen-ID: 85453