Ccl21a Antikörper (AA 24-133)

Produktnummer ABIN7600808

Dieses Anti-Ccl21a-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Ccl21a in ELISA und IHC. Geeignet für Maus und Ratte.

Kurzübersicht für Ccl21a Antikörper (AA 24-133) (ABIN7600808)

Target: Ccl21a (CCL21A) (Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A))

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Ccl21a Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Ccl21a Antikörper

Bindungsspezifität: AA 24-133

Verwendungszweck: Anti-Ccl21a Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Ccl21a Antibody Picoband® (ABIN7600808). Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Ccl21a recombinant protein (Position: S24-G133).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Dijkstra, I. M., Hulshof, S., van der Valk, P., Boddeke, H. W. G. M., Biber, K. Cutting edge: activity of human adult microglia in response to CC chemokine ligand 21. J. Immun. 172: 2744-2747, 2004. 2. Harhausen, D., Prinz, V., Ziegler, G., Gertz, K., Endres, M., Lehrach, H., Gasque, P., Botto, M., Stahel, P. F., Dirnagl, U., Nietfeld, W., Trendelenburg, G. CD93/AA4.1: a novel regulator of inflammation in murine focal cerebral ischemia. J. Immun. 184: 6407-6417, 2010. 3. Hedrick, J. A., Zlotnik, A. Identification and characterization of a novel beta chemokine containing six conserved cysteines. J. Immun. 159: 1589-1593, 1997.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu Ccl21a

Target: Ccl21a (CCL21A) (Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A))

Andere Bezeichnung: Ccl21a

Hintergrund:

Synonyms: NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2, Mtnd2, mt-Nd2, Nd2

Tissue Specificity: Ubiquitously expressed.

Background: This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).

Molekulargewicht: 14 kDa

Gen-ID: 18829

UniProt: P84444