Contactin 1 Antikörper (AA 225-979)

Produktnummer ABIN7600719

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Contactin 1 in WB, ELISA, ICC und IF. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für Contactin 1 Antikörper (AA 225-979) (ABIN7600719)

Target: Contactin 1 (CNTN1)

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Contactin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-Contactin 1 Antikörper

Bindungsspezifität: AA 225-979

Verwendungszweck: Anti-Contactin 1/CNTN1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Contactin 1/CNTN1 Antibody Picoband® (ABIN7600719). Tested in ELISA, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Contactin 1/CNTN1 recombinant protein (Position: K225-H979).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Berglund, E. O., Murai, K. K., Fredette, B., Sekerkova, G., Marturano, B., Weber, L., Mugnaini, E., Ranscht, B. Ataxia and abnormal cerebellar microorganization in mice with ablated contactin gene expression. Neuron 24: 739-750, 1999. 2. Berglund, E. O., Ranscht, B. Molecular cloning and in situ localization of the human contactin gene (CNTN1) on chromosome 12q11-q12. Genomics 21: 571-582, 1994. 3. Boyle, M. E. T., Berglund, E. O., Murai, K. K., Weber, L., Peles, E., Ranscht, B. Contactin orchestrates assembly of the septate-like junctions at the paranode in myelinated peripheral nerve. Neuron 30: 385-397, 2001.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu Contactin 1

Target: Contactin 1 (CNTN1)

Andere Bezeichnung: CNTN1

Hintergrund:

Synonyms: Ras-related protein Rab-11B, GTP-binding protein YPT3, RAB11B, YPT3

Tissue Specificity: Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas.

Background: Contactin 1, also known as CNTN1, is a protein which in humans is encoded by the CNTN1 gene. The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 135 kDa

Gen-ID: 1272

UniProt: Q12860