Cytokeratin 1 Antikörper (AA 223-439)

Produktnummer ABIN7600713

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Cytokeratin 1 in IHC, WB, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für Cytokeratin 1 Antikörper (AA 223-439) (ABIN7600713)

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cytokeratin 1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-Cytokeratin 1 Antikörper

Bindungsspezifität: AA 223-439

Verwendungszweck: Anti-Cytokeratin 1/Krt1 Antibody

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Cytokeratin 1/Krt1 Antibody. Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Mouse.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Cytokeratin 1/Krt1 recombinant protein (Position: L223-Q439).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Mouse Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Mouse Immunofluorescence, 5 μg/mL, Mouse ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Cytokeratin 1

Target: Cytokeratin 1 (KRT1) (Keratin 1 (KRT1))

Andere Bezeichnung: Krt1

Hintergrund:

Background: Keratin 1 (KRT1), also known as Cytokeratin 1, or Keratin, type II cytoskeletal 1, is a member of the keratin family. It is specifically expressed in the spinous and granular layers of the epidermis with family member keratin 10. Mutations in this gene have been associated with the variants ofbullous congenital ichthyosiform erythroderma in which the palms and soles of the feet are affected. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. And this type II cytokeratin is specifically expressed in the spinous and granular layers of the epidermis with family member KRT10 and mutations in these genes have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Gene Full Name: keratin 1

Molekulargewicht: 66 kDa

Gen-ID: 16678

UniProt: P04104