JAG2 Antikörper (AA 22-1153)

Produktnummer ABIN7600669

Der Kaninchen Polyklonal anti-JAG2 Antikörper wird verwendet zum Nachweis von JAG2 in Proben von Human. Er wurde validiert für WB und ELISA.

Kurzübersicht für JAG2 Antikörper (AA 22-1153) (ABIN7600669)

Target: JAG2 (Jagged 2 (JAG2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JAG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-JAG2 Antikörper

Bindungsspezifität: AA 22-1153

Verwendungszweck: Anti-Jagged 2/JAG2 Antibody

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Homologie: Human JAG2 shares 91.1%,91% amino acid (aa) sequence identity with mouse,rat JAG2,respectively.

Produktmerkmale: Anti-Jagged 2/JAG2 Antibody. Tested in ELISA, WB applications. This antibody reacts with Human.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Jagged 2/JAG2 recombinant protein (Position: Q22-N1153). Human JAG2 shares 91.1% and 91% amino acid (aa) sequence identity with mouse and rat JAG2, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human ELISA, 0.1-0.5 μg/mL, -

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu JAG2

Target: JAG2 (Jagged 2 (JAG2))

Andere Bezeichnung: JAG2

Hintergrund:

Background: Protein jagged-2, also known as SER2, is a protein that in humans is encoded by the JAG2 gene. It is mapped to 14q32.33. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Notch ligands Delta1 and JAG2 are subject to presenilin-dependent, intramembranous gamma-secretase processing, resulting in the production of soluble intracellular derivatives. JAG2 can promote the growth and dissemination of uveal melanoma cells.

Gene Full Name: jagged canonical Notch ligand 2

Molekulargewicht: 130 kDa

Gen-ID: 3714

UniProt: Q9Y219

Pathways: Notch Signalweg, Sensory Perception of Sound