MANSC1 Antikörper (AA 21-337)

Produktnummer ABIN7600615

Der Kaninchen Polyklonal Anti-MANSC1-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, MANSC1 in Proben von Human zu detektieren.

Kurzübersicht für MANSC1 Antikörper (AA 21-337) (ABIN7600615)

Target: MANSC1 (MANSC Domain Containing 1 (MANSC1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MANSC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MANSC1 Antikörper

Bindungsspezifität: AA 21-337

Verwendungszweck: Anti-MANSC1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-MANSC1 Antibody Picoband® (ABIN7600615). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MANSC1 recombinant protein (Position: L21-N337).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Clark, H. F. , Gurney, A. L. , Abaya, E. , Baker, K. , Baldwin, D. , & Brush, J. , et al. (2003). The secreted protein discovery initiative (spdi), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. Genome Research, 13(10), 2265-2276. 2. Ezh2 depletion potentiates myc degradation inhibiting neuroblastoma and small cell carcinoma tumor formation. Nature Communications. 3. Luck, K. , Kim, D. K. , Lambourne, L. , Spirohn, K. , & Calderwood, M. A. . (2020). A reference map of the human binary protein interactome. Nature, 580(D1).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu MANSC1

Target: MANSC1 (MANSC Domain Containing 1 (MANSC1))

Andere Bezeichnung: MANSC1

Hintergrund:

Synonyms: Kelch repeat and BTB domain-containing protein 2, BTB and kelch domain-containing protein 1, KBTBD2, BKLHD1, KIAA1489

Tissue Specificity: Detected in liver, skeletal muscle, kidney, pancreas, spleen, thyroid, testis, ovary, small intestine and colon.

Background: MANSC1 (MANSC domain-containing protein 1), also known as LOH12CR3 (Loss of heterozygosity 12 chromosomal region 3 protein), is a 414 amino acid single-pass membrane protein. Expressed throughout the body, MANSC1 contains one MANSC domain and is encoded by a gene that is located on chromosome 12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12, including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction.

Molekulargewicht: 62 kDa

Gen-ID: 54682

UniProt: Q9H8J5