LY6E Antikörper (AA 21-101)

Produktnummer ABIN7600591

Der Kaninchen Polyklonal Anti-LY6E-Antikörper wurde für ELISA, WB, IHC und FACS validiert. Er ist geeignet, LY6E in Proben von Human zu detektieren.

Kurzübersicht für LY6E Antikörper (AA 21-101) (ABIN7600591)

Target: LY6E (Lymphocyte Antigen 6 Complex, Locus E (LY6E))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LY6E Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-LY6E Antikörper

Bindungsspezifität: AA 21-101

Verwendungszweck: Anti-LY6E/SCA-2 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-LY6E/SCA-2 Antibody Picoband® (ABIN7600591). Tested in ELISA, Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human LY6E/SCA-2 recombinant protein (Position: L21-S101).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Mao, M., Yu, M., Tong, J.-H., Ye, J., Zhu, J., Huang, Q.-H., Fu, G., Yu, L., Zhao, S.-Y., Waxman, S., Lanotte, M., Wang, Z.-Y., Tan, J.-Z., Chan, S.-J., Chen, Z. RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell. Proc. Nat. Acad. Sci. 93: 5910-5914, 1996. 2. Shan, X., Bourdeau, A., Rhoton, A., Wells, D. E., Cohen, E. H., Landgraf, B. E., Palfree, R. G. E. Characterization and mapping to human chromosome 8q24.3 of Ly-6-related gene 9804 encoding an apparent homologue of mouse TSA-1. J. Immun. 160: 197-208, 1998.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu LY6E

Target: LY6E (Lymphocyte Antigen 6 Complex, Locus E (LY6E))

Andere Bezeichnung: LY6E

Hintergrund:

Synonyms: Mediator of RNA polymerase II transcription subunit 20, Mediator complex subunit 20, TRF-proximal protein homolog, hTRFP, MED20, TRFP,

Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Background: Lymphocyte antigen 6E is a protein that in humans is encoded by the LY6E gene. Increased expression of Ly6E is associated with poor survival outcome in multiple malignancies as determined by a survey of more than 130 published clinical studies of gene expression studies on cancer tissue samples and adjacent normal tissues. Ly6E is associated with drug resistance and tumor immune escape in breast cancer. Further research is required to validate Ly6E for translation research.

Molekulargewicht: 14 kDa

Gen-ID: 4061

UniProt: Q16553

Pathways: Hormone Transport