Anti-PKN3 Antibody Picoband® (ABIN7600512). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Aufreinigung
Immunogen affinity purified.
Immunogen
E.coli-derived human PKN3 recombinant protein (Position: E2-P889). Human PKN3 shares 83.7% amino acid (aa) sequence identity with mouse PKN3.
PKN3
Reaktivität: Human
WB
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, - 1. Hartz, P. A. Personal Communication. Baltimore, Md. 1/23/2007. 2. Leenders, F., Mopert, K., Schmiedeknecht, A., Santel, A., Czauderna, F., Aleku, M., Penschuck, S., Dames, S., Sternberger, M., Rohl, T., Wellmann, A., Arnold, W., Giese, K., Kaufmann, J., Klippel, A. PKN3 is required for malignant prostate cell growth downstream of activated PI 3-kinase. EMBO J. 23: 3303-3313, 2004. 3. Oishi, K., Mukai, H., Shibata, H., Takahashi, M., Ona, Y. Identification and characterization of PKN-beta, a novel isoform of protein kinase PKN: expression and arachidonic acid dependency are different from those of PKN-alpha. Biochem. Biophys. Res. Commun. 261: 808-814, 1999.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Rekonstitution
Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
Target
PKN3
(Protein Kinase N3 (PKN3))
Andere Bezeichnung
PKN3
Hintergrund
Protein kinase N3 is a serine/threonine protein kinase and one of three PKN isoforms (PKN1, PKN2, PKN3) encoded by independent genes. PKN3 has been identified as an effector that mediates malignant prostate cell growth and is activated by PI3-kinase.