MVP Antikörper (AA 2-259) (DyLight 488)

Produktnummer ABIN7600482

Dieses Maus Monoklonal-Antikörper erkennt spezifisch MVP in FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für MVP Antikörper (AA 2-259) (DyLight 488) (ABIN7600482)

Target: MVP (Major Vault Protein (MVP))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MVP Antikörper ist konjugiert mit DyLight 488

Applikation: Flow Cytometry (FACS)

Klon: 8B12

Produktdetails anti-MVP Antikörper (DyLight 488)

Bindungsspezifität: AA 2-259

Verwendungszweck: Anti-Human MVP DyLight® 488 conjugated Antibody(monoclonal, 8B12)

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Human MVP DyLight® 488 conjugated Antibody (monoclonal, 8B12) -Dyl488. Tested in Flow Cytometry applications. This antibody reacts with Human.

Immunogen: E. coli-derived human MVP recombinant protein (Position: A2-H259).

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, human
1. "Entrez Gene: MVP major vault protein". 2. Izquierdo MA, Scheffer GL, Flens MJ, Schroeijers AB, van der Valk P, Scheper RJ (Jun 1996). "Major vault protein LRP-related multidrug resistance". European Journal of Cancer. 32A (6): 979-84.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Details zu MVP

Target: MVP (Major Vault Protein (MVP))

Andere Bezeichnung: MVP

Hintergrund:

Synonyms: Major vault protein, MVP, Lung resistance-related protein, MVP, LRP

Background: Major vault protein is a protein that in humans is encoded by the MVP gene. This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.

Molekulargewicht: 39 kDa

Gen-ID: 9961

UniProt: Q14764