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SP7 Antikörper (AA 2-241)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SP7 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.
Produktnummer ABIN7600476

Kurzübersicht für SP7 Antikörper (AA 2-241) (ABIN7600476)

Target

Alle SP7 Antikörper anzeigen
SP7 (Sp7 Transcription Factor (SP7))

Reaktivität

  • 22
  • 8
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Human, Maus, Ratte

Wirt

  • 20
  • 5
Kaninchen

Klonalität

  • 20
  • 5
Polyklonal

Konjugat

  • 18
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SP7 Antikörper ist unkonjugiert

Applikation

  • 17
  • 12
  • 7
  • 6
  • 5
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 2-241

    Verwendungszweck

    Anti-Sp7/Osterix Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-Sp7/Osterix Antibody Picoband® (ABIN7600476). Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human Sp7/Osterix recombinant protein (Position: A2-E241).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
    ELISA, 0.1-0.5 μg/mL, -
    1. Fiscaletti, M., Biggin, A., Bennetts, B., Wong, K., Briody, J., Pacey, V., Birman, C., Munns, C. F. Novel variant in Sp7/Osx associated with recessive osteogenesis imperfecta with bone fragility and hearing impairment. Bone 110: 66-75, 2018. 2. Gao, Y., Jheon, A., Nourkeyhani, H., Kobayashi, H., Ganss, B. Molecular cloning, structure, expression, and chromosomal localization of the human Osterix (SP7) gene. Gene 341: 101-110, 2004. 3. Koga, T., Matsui, Y., Asagiri, M., Kodama, T., de Crombrugghe, B., Nakashima, K., Takayanagi, H. NFAT and Osterix cooperatively regulate bone formation. Nature Med. 11: 880-885, 2005.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target

    SP7 (Sp7 Transcription Factor (SP7))

    Andere Bezeichnung

    SP7

    Hintergrund

    Synonyms: Deleted in azoospermia-like, DAZ homolog, DAZ-like autosomal, Deleted in azoospermia-like 1, SPGY-like-autosomal, DAZL, DAZH, DAZL1, DAZLA, SPGYLA

    Background: Transcription factor Sp7, also called Osterix (Osx), is a protein that in humans is encoded by the SP7 gene. This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.

    Molekulargewicht

    45 kDa

    Gen-ID

    121340
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