NCOA5 Antikörper (AA 191-560)

Produktnummer ABIN7600433

Dieses Anti-NCOA5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NCOA5 in ELISA, WB, IHC, IF, FACS und ICC. Geeignet für Human, Maus und Ratte.

Kurzübersicht für NCOA5 Antikörper (AA 191-560) (ABIN7600433)

Target: NCOA5 (Nuclear Receptor Coactivator 5 (NCOA5))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NCOA5 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Produktdetails anti-NCOA5 Antikörper

Bindungsspezifität: AA 191-560

Verwendungszweck: Anti-NCOA5 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-NCOA5 Antibody Picoband® (ABIN7600433). Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human NCOA5 recombinant protein (Position: R191-Q560).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gao, S., Li, A., Liu, F., Chen, F., Williams, M., zhang, C., Kelley, Z., Wu, C.-L., Luo, R., Xiao, H. NCOA5 haploinsufficiency results in glucose intolerance and subsequent hepatocellular carcinoma. Cancer Cell 24: 725-737, 2013. 2. Sauve, F., McBroom, L. D. B., Gallant, J., Moraitis, A. N., Labrie, F., Giguere, V. CIA, a novel estrogen receptor coactivator with a bifunctional nuclear receptor interacting determinant. Molec. Cell. Biol. 21: 343-353, 2001.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu NCOA5

Target: NCOA5 (Nuclear Receptor Coactivator 5 (NCOA5))

Andere Bezeichnung: NCOA5

Hintergrund:

Synonyms: Protein SOX-15, Protein SOX-12, Protein SOX-20, SOX15, SOX12, SOX20, SOX26, SOX27

Tissue Specificity: Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.

Background: Nuclear receptor coactivator 5 (NCOA5), also known as coactivator independent of AF-2 function (CIA), is a protein that in humans is encoded by the NCOA5 gene. This gene encodes a coregulator for the alpha and beta estrogen receptors and the orphan nuclear receptor NR1D2. The protein localizes to the nucleus, and is thought to have both coactivator and corepressor functions. Its interaction with nuclear receptors is independent of the AF2 domain on the receptors, which is known to regulate interaction with other coreceptors. Several alternatively spliced transcript variants have been found for this gene.

Molekulargewicht: 66 kDa

Gen-ID: 57727