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PHTF1 Antikörper (AA 188-430)

PHTF1 Reaktivität: Human WB, ELISA, FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7600390
  • Target Alle PHTF1 Antikörper anzeigen
    PHTF1 (Putative Homeodomain Transcription Factor 1 (PHTF1))
    Bindungsspezifität
    • 2
    • 2
    AA 188-430
    Reaktivität
    • 12
    • 7
    Human
    Wirt
    • 7
    • 5
    Kaninchen
    Klonalität
    • 10
    • 2
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PHTF1 Antikörper ist unkonjugiert
    Applikation
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Verwendungszweck
    Anti-PHTF1 Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins.
    Produktmerkmale
    Anti-PHTF1 Antibody Picoband® (ABIN7600390). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human PHTF1 recombinant protein (Position: I188-Q430).
    Isotyp
    IgG
    Top Product
    Discover our top product PHTF1 Primärantikörper
  • Applikationshinweise
    Western blot, 0.25-0.5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Manuel, A., Beaupain, D., Romeo, P. H., Raich, N. Molecular characterization of a novel gene family (PHTF) conserved from Drosophila to mammals. Genomics 64: 216-220, 2000. 2. Raich, N., Mattei, M. G., Romeo, P. H., Beaupain, D. PHTF, a novel atypical homeobox gene on chromosome 1p13, is evolutionarily conserved. Genomics 59: 108-109, 1999.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target
    PHTF1 (Putative Homeodomain Transcription Factor 1 (PHTF1))
    Andere Bezeichnung
    PHTF1 (PHTF1 Produkte)
    Hintergrund

    Synonyms: Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/I, Histone H3/j, Histone H3/k, Histone H3/l, HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J, H3FJ

    Tissue Specificity: Expressed in fetal brain, fetal lung, fetal liver, heart, brain, placenta, lung, liver, muscle, kidney and pancreas.

    Background: HTF1 (putative homeodomain transcription factor 1), also known as PHTF, is a potential transcription regulator. It is a ubiquitously expressed integral, multipass membrane protein with predominant expression in testis. PHTF1 is associated with the ER (endoplasmic reticulum) and contains one bHLH (basic helix-loop-helix) domain. It is present in the cell during meiosis and spermiogenesis but, by the end of spermiogenesis, is released from the mature cell within the residual bodies. This implies that PHTF1 may play a role in the spermatozoa maturation process. In addition, PHTF1 is believed to interact with FEM1B and may be responsible for recruiting FEM1B to the surface of the ER membrane. This suggests that PHTF1 acts as a sequestering or anchoring protein for FEM1B. Two PHTF1 isoforms exist due to alternate splicing events. Isoform 2 is the shorter form and lacks the amino acid residues 648 to 762.

    Molekulargewicht
    100 kDa
    Gen-ID
    10745
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