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STAMBP Antikörper (AA 187-424)

Dieses Anti-STAMBP-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von STAMBP in WB, ELISA, IHC, IF, ICC und FACS. Geeignet für Human, Maus, Ratte und Affe.
Produktnummer ABIN7600388

Kurzübersicht für STAMBP Antikörper (AA 187-424) (ABIN7600388)

Target

Alle STAMBP Antikörper anzeigen
STAMBP (STAM Binding Protein (STAMBP))

Reaktivität

  • 42
  • 32
  • 21
  • 6
  • 5
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
Human, Maus, Ratte, Affe

Wirt

  • 54
  • 4
Kaninchen

Klonalität

  • 55
  • 3
Polyklonal

Konjugat

  • 27
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser STAMBP Antikörper ist unkonjugiert

Applikation

  • 33
  • 19
  • 16
  • 13
  • 13
  • 7
  • 6
  • 4
  • 3
  • 3
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 15
    • 8
    • 8
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 187-424

    Verwendungszweck

    Anti-STAMBP Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins

    Produktmerkmale

    Anti-STAMBP Antibody Picoband® (ABIN7600388). Tested in WB, IHC, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human STAMBP recombinant protein (Position: K187-R424). Human STAMBP shares 79% and 79.8% amino acid (aa) sequence identity with mouse and rat STAMBP, respectively.

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Monkey, Mouse
    Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL
    1. Carter, M. T., Geraghty, M. T., De La Cruz, L., Reichard, R. R., Boccuto, L., Schwartz, C. E., Clericuzio, C. L. A new syndrome with multiple capillary malformations, intractable seizures, and brain and limb anomalies. Am. J. Med. Genet. 155A: 301-306, 2011. 2. Ishii, N., Owada, Y., Yamada, M., Miura, S., Murata, K., Asao, H., Kondo, H., Sugamura, K. Loss of neurons in the hippocampus and cerebral cortex of AMSH-deficient mice. Molec. Cell. Biol. 21: 8626-8637, 2001. 3. Isidor, B., Barbarot, S., Beneteau, C., Le Caignec, C., David, A. Multiple capillary skin malformations, epilepsy, microcephaly, mental retardation, hypoplasia of the distal phalanges: report of a new case and further delineation of a new syndrome. (Letter) Am. J. Med. Genet. 155A: 1458-1460, 2011.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    STAMBP (STAM Binding Protein (STAMBP))

    Andere Bezeichnung

    STAMBP

    Hintergrund

    Synonyms: STAMBP, AMSH, STAM-binding protein, EC 3.4.19.-, Associated molecule with the SH3 domain of STAM, Endosome-associated ubiquitin isopeptidase

    Background: Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules. One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth. The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

    Molekulargewicht

    48 kDa

    Gen-ID

    10617

    UniProt

    O95630
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