Moesin Antikörper (AA 184-568)

Produktnummer ABIN7600379

Dieses Anti-Moesin-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von Moesin in WB, IHC, IF, FACS und ICC. Geeignet für Human, Ratte, Maus und Affe.

Kurzübersicht für Moesin Antikörper (AA 184-568) (ABIN7600379)

Target: Moesin (MSN)

Reaktivität: Human, Ratte, Maus, Affe

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Moesin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: 8D4

Produktdetails anti-Moesin Antikörper

Bindungsspezifität: AA 184-568

Verwendungszweck: Anti-Moesin/MSN Antibody Picoband® (monoclonal, 8D4)

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Moesin/MSN Antibody Picoband® (monoclonal, 8D4) (ABIN7600379). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Moesin/MSN recombinant protein (Position: R184-K568).

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat, Monkey
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x⁶ cells, Human
1. Lankes WT, Furthmayr H (Oct 1991). "Moesin: a member of the protein 4.1-talin-ezrin family of proteins". Proc. Natl. Acad. Sci. U.S.A. 88 (19): 8297-301. 2. Amieva MR, Furthmayr H (Sep 1995). "Subcellular localization of moesin in dynamic filopodia, retraction fibers, and other structures involved in substrate exploration, attachment, and cell-cell contacts". Exp. Cell Res. 219 (1): 180-96. 3. Serrador JM, Nieto M, Alonso-Lebrero JL, del Pozo MA, Calvo J, Furthmayr H, Schwartz-Albiez R, Lozano F, González-Amaro R, Sánchez-Mateos P, Sánchez-Madrid F (Jun 1998). "CD43 interacts with moesin and ezrin and regulates its redistribution to the uropods of T lymphocytes at the cell-cell contacts". Blood. 91 (12): 4632-44.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu Moesin

Target: Moesin (MSN)

Andere Bezeichnung: MSN

Hintergrund:

Synonyms: SRK, STD, TZK, ZAP70, ZAP-70, ZAP 70, P43403

Tissue Specificity: Expressed in T- and natural killer cells. Also present in early thymocytes and pro/pre B-cells.

Background: Moesin is a protein that in humans is encoded by the MSN gene. It is mapped to Xq12. Moesin (for membrane-organizing extension spike protein) is a member of the ERM family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers between plasma membranes and actin-based cytoskeletons. Moesin is localized to filopodia and other membranous protrusions that are important for cell-cell recognition and signaling and for cell movement.

Molekulargewicht: 78 kDa

Gen-ID: 4478

UniProt: P26038

Pathways: Asymmetric Protein Localization