RBM28 Antikörper (AA 18-584)

Produktnummer ABIN7600351

Der Kaninchen Polyklonal Anti-RBM28-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, RBM28 in Proben von Human zu detektieren.

Kurzübersicht für RBM28 Antikörper (AA 18-584) (ABIN7600351)

Target: RBM28 (RNA Binding Motif Protein 28 (RBM28))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RBM28 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-RBM28 Antikörper

Bindungsspezifität: AA 18-584

Verwendungszweck: Anti-RBM28 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-RBM28 Antibody Picoband® (ABIN7600351). Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human RBM28 recombinant protein (Position: E18-K584).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Damianov, A., Kann, M., Lane, W. S., Bindereif, A. Human RBM28p protein is a specific nucleolar component of the spliceosomal snRNPs. Biol. Chem. 387: 1455-1460, 2006. 2. Gross, M. B. Personal Communication. Baltimore, Md. 10/30/2017. 3. Nousbeck, J., Spiegel, R., Ishida-Yamamoto, A., Indelman, M., Shani-Adir, A., Adir, N., Lipkin, E., Bercovici, S., Geiger, D., van Steensel, M. A., Steijlen, P. M., Bergman, R., Bindereif, A., Choder, M., Shalev, S., Sprecher, E. Alopecia, neurological defects, and endocrinopathy syndrome caused by decreased expression of RBM28, a nucleolar protein associated with ribosome biogenesis. Am. J. Hum. Genet. 82: 1114-1121, 2008.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu RBM28

Target: RBM28 (RNA Binding Motif Protein 28 (RBM28))

Andere Bezeichnung: RBM28

Hintergrund:

Synonyms: B-cell differentiation antigen CD72, Lyb-2, CD72, CD72

Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Background: RNA-binding protein 28 is a protein that in humans is encoded by the RBM28 gene. The protein encoded by this gene is a specific nucleolar component of the spliceosomal small nuclear ribonucleoprotein (snRNP)complexes . It specifically associates with U1, U2, U4, U5, and U6 small nuclear RNAs (snRNAs), possibly coordinating their transition through the nucleolus. Mutation in this gene causes alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome), a pleiotropic and clinically heterogeneous disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 100 kDa

Gen-ID: 55131

Pathways: SARS-CoV-2 Protein Interaktom