MOAP1 Antikörper (AA 18-341)
Kurzübersicht für MOAP1 Antikörper (AA 18-341) (ABIN7600332)
Target
Alle MOAP1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 18-341
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Verwendungszweck
- Anti-MOAP1 Antibody Picoband®
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Kreuzreaktivität (Details)
- No cross-reactivity with other proteins.
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Produktmerkmale
- Anti-MOAP1 Antibody Picoband® (ABIN7600332). Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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Aufreinigung
- Immunogen affinity purified.
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Immunogen
- E.coli-derived human MOAP1 recombinant protein (Position: R18-L341).
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Isotyp
- IgG
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Applikationshinweise
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Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry, 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Baksh, S., Tommasi, S., Fenton, S., Yu, V. C., Martins, L. M., Pfeifer, G. P., Latif, F., Downward, J., Neel, B. G. The tumor suppressor RASSF1A and MAP-1 link death receptor signaling to Bax conformational change and cell death. Molec. Cell 18: 637-650, 2005. 2. Gross, M. B. Personal Communication. Baltimore, Md. 2/27/2014. 3. Tan, K. O., Tan, K. M. L., Chan, S.-L., Yee, K. S. Y., Bevort, M., Ang, K. C., Yu, V. C. MAP-1, a novel proapoptotic protein containing a BH3-like motif that associates with Bax through its Bcl-2 homology domains. J. Biol. Chem. 276: 2802-2807, 2001. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Konzentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
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- MOAP1 (Modulator of Apoptosis 1 (MOAP1))
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Andere Bezeichnung
- MOAP1
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Hintergrund
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Synonyms: BMP and activin membrane-bound inhibitor homolog, Non-metastatic gene A protein, Putative transmembrane protein, NMA, BAMBI, NMA
Tissue Specificity: Expressed in adult liver.
Background: Modulator of apoptosis 1 is a protein that in humans is encoded by the MOAP1 gene. The protein encoded by this gene was identified by its interaction with apoptosis regulator BAX protein. This protein contains a Bcl-2 homology 3 (BH3)-like motif, which is required for the association with BAX. When overexpressed, this gene has been shown to mediate caspase-dependent apoptosis.
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Molekulargewicht
- 35 kDa
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Gen-ID
- 64112
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Pathways
- Positive Regulation of Endopeptidase Activity
Target
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