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STRIP2 Antikörper (AA 173-507)

Der Kaninchen Polyklonal Anti-STRIP2-Antikörper wurde für WB, IHC, ELISA und FACS validiert. Er ist geeignet, STRIP2 in Proben von Human, Maus und Ratte zu detektieren.
Produktnummer ABIN7600294

Kurzübersicht für STRIP2 Antikörper (AA 173-507) (ABIN7600294)

Target

Alle STRIP2 Antikörper anzeigen
STRIP2 (Striatin Interacting Protein 2 (STRIP2))

Reaktivität

Human, Maus, Ratte

Wirt

  • 11
Kaninchen

Klonalität

  • 11
Polyklonal

Konjugat

  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
Dieser STRIP2 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 10
    • 3
    AA 173-507

    Verwendungszweck

    Anti-FAM40B/STRIP2 Antibody Picoband®

    Produktmerkmale

    Anti-FAM40B/STRIP2 Antibody Picoband® (ABIN7600294). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human FAM40B/STRIP2 recombinant protein (Position: H173-Q507). Human STRIP2 shares 96.4% amino acid (aa) sequence identity with mouse STRIP2.
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human, Rat
    Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Gross, M. B. Personal Communication. Baltimore, Md. 3/22/2018. 2. Kemp, H. A., Sprague, G. F., Jr. Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae. Molec. Cell. Biol. 23: 1750-1763, 2003. 3. Madsen, C. D., Hooper, S., Tozluoglu, M., Bruckbauer, A., Fletcher, G., Erler, J. T., Bates, P. A., Thompson, B., Sahai, E. STRIPAK components determine mode of cancer cell migration and metastasis. Nature Cell Biol. 17: 68-80, 2015.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    STRIP2 (Striatin Interacting Protein 2 (STRIP2))

    Andere Bezeichnung

    STRIP2

    Hintergrund

    The STRIP2 gene encodes a protein known as striatin-interacting protein 2, which interacts with striatin, a scaffolding protein involved in diverse cellular processes such as signaling, cell adhesion, and transcriptional regulation. STRIP2 is implicated in cardiac development and function, where it modulates cardiac hypertrophy, contractility, and arrhythmogenesis. Additionally, it plays roles in neuronal development and synaptic plasticity in the brain. Dysregulation of STRIP2 expression or function has been associated with various cardiovascular disorders, including hypertrophic cardiomyopathy and arrhythmias, as well as neurodevelopmental disorders such as autism spectrum disorders. Elucidating the molecular mechanisms underlying STRIP2 function is essential for understanding its physiological roles in cardiac and neural tissues and its potential implications for disease pathology and therapeutic targeting.

    Molekulargewicht

    100 kDa

    Gen-ID

    57464
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