STRIP2 Antikörper (AA 173-507)

Produktnummer ABIN7600294

Produktdetails anti-STRIP2 Antikörper

Target: STRIP2 (Striatin Interacting Protein 2 (STRIP2))

Bindungsspezifität: AA 173-507

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STRIP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS)

Verwendungszweck: Anti-FAM40B/STRIP2 Antibody Picoband®

Produktmerkmale: Anti-FAM40B/STRIP2 Antibody Picoband® (ABIN7600294). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human FAM40B/STRIP2 recombinant protein (Position: H173-Q507). Human STRIP2 shares 96.4% amino acid (aa) sequence identity with mouse STRIP2.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Gross, M. B. Personal Communication. Baltimore, Md. 3/22/2018. 2. Kemp, H. A., Sprague, G. F., Jr. Far3 and five interacting proteins prevent premature recovery from pheromone arrest in the budding yeast Saccharomyces cerevisiae. Molec. Cell. Biol. 23: 1750-1763, 2003. 3. Madsen, C. D., Hooper, S., Tozluoglu, M., Bruckbauer, A., Fletcher, G., Erler, J. T., Bates, P. A., Thompson, B., Sahai, E. STRIPAK components determine mode of cancer cell migration and metastasis. Nature Cell Biol. 17: 68-80, 2015.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu STRIP2

Target: STRIP2 (Striatin Interacting Protein 2 (STRIP2))

Andere Bezeichnung: STRIP2 (STRIP2 Produkte)

Hintergrund: The STRIP2 gene encodes a protein known as striatin-interacting protein 2, which interacts with striatin, a scaffolding protein involved in diverse cellular processes such as signaling, cell adhesion, and transcriptional regulation. STRIP2 is implicated in cardiac development and function, where it modulates cardiac hypertrophy, contractility, and arrhythmogenesis. Additionally, it plays roles in neuronal development and synaptic plasticity in the brain. Dysregulation of STRIP2 expression or function has been associated with various cardiovascular disorders, including hypertrophic cardiomyopathy and arrhythmias, as well as neurodevelopmental disorders such as autism spectrum disorders. Elucidating the molecular mechanisms underlying STRIP2 function is essential for understanding its physiological roles in cardiac and neural tissues and its potential implications for disease pathology and therapeutic targeting.

Molekulargewicht: 100 kDa

Gen-ID: 57464