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NAF1 Antikörper (AA 173-340)

Dieses Anti-NAF1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NAF1 in WB und ELISA. Geeignet für Human.
Produktnummer ABIN7600289

Kurzübersicht für NAF1 Antikörper (AA 173-340) (ABIN7600289)

Target

Alle NAF1 Antikörper anzeigen
NAF1 (Nuclear ssembly factor 1 ribonucleoprotein (NAF1))

Reaktivität

  • 3
  • 1
  • 1
Human

Wirt

  • 3
Kaninchen

Klonalität

  • 3
Polyklonal

Konjugat

  • 3
Dieser NAF1 Antikörper ist unkonjugiert

Applikation

  • 2
  • 1
  • 1
Western Blotting (WB), ELISA
  • Bindungsspezifität

    • 1
    • 1
    AA 173-340

    Verwendungszweck

    Anti-NAF1 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-NAF1 Antibody Picoband® (ABIN7600289). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human NAF1 recombinant protein (Position: K173-E340).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.25-0.5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Hartz, P. A. Personal Communication. Baltimore, Md. 2/7/2018. 2. Hoareau-Aveilla, C., Bonoli, M., Caizergues-Ferrer, M., Henry, Y. hNaf1 is required for accumulation of human box H/ACA snoRNPs, scaRNPs, and telomerase. RNA 12: 832-840, 2006. 3. Stanley, S. E., Gable, D. L., Wagner, C. L., Carlile, T. M., Hanumanthu, V. S., Podlevsky, J. D., Khalil, S. E., DeZern, A. E., Rojas-Duran, M. F., Applegate, C. D., Alder, J. K., Parry, E. M., Gilbert, W. V., Armanios, M. Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema. Sci. Transl. Med. 8: 351ra107, 2016. Note: Electronic Article.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    NAF1 (Nuclear ssembly factor 1 ribonucleoprotein (NAF1))

    Andere Bezeichnung

    NAF1

    Hintergrund

    Synonyms: Homeobox protein SIX3,Sine oculis homeobox homolog 3,SIX3,

    Tissue Specificity: Highly expressed in placenta, lung, kidney, testis and ovary. Weakly expressed in spleen and thymus. Not expressed in peripheral blood lymphocytes. Detected in hippocampus.

    Background: Enables identical protein binding activity and telomerase RNA binding activity. Involved in regulation of nucleobase-containing compound metabolic process, ribosome biogenesis, and telomerase holoenzyme complex assembly. Located in nucleoplasm. Part of sno(s)RNA-containing ribonucleoprotein complex.

    Molekulargewicht

    70 kDa

    Gen-ID

    92345
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