KRT4 Antikörper (AA 170-427)

Produktnummer ABIN7600283

Dieses Anti-KRT4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von KRT4 in WB, IHC, ELISA und IF. Geeignet für Human.

Kurzübersicht für KRT4 Antikörper (AA 170-427) (ABIN7600283)

Target: KRT4 (Keratin 4 (KRT4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KRT4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-KRT4 Antikörper

Bindungsspezifität: AA 170-427

Verwendungszweck: Anti-Cytokeratin 4/KRT4 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-Cytokeratin 4/KRT4 Antibody Picoband® (ABIN7600283). Tested in ELISA, IF, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Cytokeratin 4/KRT4 recombinant protein (Position: N170-S427).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Immunofluorescence, 5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Barletta, C., Batticane, N., Ragusa, R. M., Leube, R., Peschle, C., Romano, V. Subchromosomal localization of two human cytokeratin genes (KRT4 and KRT15) by in situ hybridization. Cytogenet. Cell Genet. 54: 148-150, 1990. 2. Barletta, C., Batticane, N., Ragusa, R. M., Leube, R. E., Franke, W. W., Peschle, C., Romano, V. Sub-chromosomal localization of human cytokeratin 4, 15, and 19 genes. (Abstract) Cytogenet. Cell Genet. 51: 958 only, 1989. 3. Chao, S.-C., Tsai, Y.-M., Yang, M.-H., Lee, J. Y.-Y. A novel mutation in the keratin 4 gene causing white sponge naevus. Brit. J. Derm. 148: 1125-1128, 2003.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu KRT4

Target: KRT4 (Keratin 4 (KRT4))

Andere Bezeichnung: KRT4

Hintergrund:

Synonyms: BAG family molecular chaperone regulator 5,BAG-5,Bcl-2-associated athanogene 5,BAG5,KIAA0873,

Tissue Specificity: Expressed in all tissues examined with lower levels in brain and testis.

Background: Keratin, type I cytoskeletal 4 also known as cytokeratin-4 (CK-4) or keratin-4 (K4) is a protein that in humans is encoded by the KRT4 gene. The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in differentiated layers of the mucosal and esophageal epithelia with family member KRT13. Mutations in these genes have been associated with White Sponge Nevus, characterized by oral, esophageal, and anal leukoplakia. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

Molekulargewicht: 56 kDa

Gen-ID: 3851

UniProt: P19013