LNPEP Antikörper (AA 17-994)

Produktnummer ABIN7600279

Der Kaninchen Polyklonal Anti-LNPEP-Antikörper wurde für WB, IHC und ELISA validiert. Er ist geeignet, LNPEP in Proben von Human, Ratte und Maus zu detektieren.

Kurzübersicht für LNPEP Antikörper (AA 17-994) (ABIN7600279)

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LNPEP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Produktdetails anti-LNPEP Antikörper

Bindungsspezifität: AA 17-994

Verwendungszweck: Anti-LNPEP Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-LNPEP Antibody Picoband® (ABIN7600279). Tested in ELISA, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human LNPEP recombinant protein (Position: E17-T994).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human, Mouse, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Beckman, L., Beckman, G., Mi, M. P., De Simone, J. The human placental amino acid naphthylamidases: their molecular interrelations and correlations with perinatal factors. Hum. Hered. 19: 249-257, 1969. 2. Beckman, L., Bjorling, G., Christodoulou, C. Pregnancy enzymes and placental polymorphism. II. Leucine aminopeptidase. Acta Genet. Statist. Med. 16: 122-131, 1966. 3. Horio, J., Nomura, S., Okada, M., Katsumata, Y., Nakanishi, Y., Kumano, Y., Takami, S., Kinoshita, M., Tsujimoto, M., Nakazato, H., Mizutani, S. Structural organization of the 5-prime-end and chromosomal assignment of human placental leucine aminopeptidase/insulin-regulated membrane aminopeptidase gene. Biochem. Biophys. Res. Commun. 262: 269-274, 1999.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu LNPEP

Target: LNPEP (Leucyl/cystinyl Aminopeptidase (LNPEP))

Andere Bezeichnung: LNPEP

Hintergrund:

Synonyms: Sentrin-specific protease 6, SUMO-1-specific protease 1, Sentrin/SUMO-specific protease SENP6, SENP6, KIAA0797, SSP1, SUSP1, FKSG6

Tissue Specificity: Expressed in many tissues, highest levels in skeletal muscle.

Background: Leucyl/cystinyl aminopeptidase, also known as cystinyl aminopeptidase (CAP), insulin-regulated aminopeptidase (IRAP), human placental leucine aminopeptidase (PLAP), oxytocinase, and vasopressinase, is an enzyme of the aminopeptidase group that in humans is encoded by the LNPEP gene. This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms.

Molekulargewicht: 117 kDa

Gen-ID: 4012

Pathways: Regulation of long-term Neuronal Synaptic Plasticity