LSM11 Antikörper (AA 17-360)

Produktnummer ABIN7600265

Dieses Anti-LSM11-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von LSM11 in WB und ELISA. Geeignet für Human und Ratte.

Kurzübersicht für LSM11 Antikörper (AA 17-360) (ABIN7600265)

Target: LSM11 (LSM11, U7 Small Nuclear RNA Associated (LSM11))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LSM11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-LSM11 Antikörper

Bindungsspezifität: AA 17-360

Verwendungszweck: Anti-LSM11 Antibody Picoband®

Produktmerkmale: Anti-LSM11 Antibody Picoband® (ABIN7600265). Tested in WB, ELISA applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human LSM11 recombinant protein (Position: A17-Q360). Human LSM11 shares 88.4% amino acid (aa) sequence identity with mouse LSM11.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Rat
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 3/15/2018. 2. Pillai, R. S., Grimmler, M., Meister, G., Will, C. L., Luhrmann, R., Fischer, U., Schumperli, D. Unique Sm core structure of U7 snRNPs: assembly by a specialized SMN complex and the role of a new component, Lsm11, in histone RNA processing. Genes Dev. 17: 2321-2333, 2003. 3. Uggenti, C., Lepelley, A., Depp, M., Badrock, A. P., Rodero, M. P., El-Daher, M.-T., Rice, G. I., Dhir, S., Wheeler, A. P., Dhir, A., Albawardi, W., Fremond, M.-L., and 44 others. cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing. Nature Genet. 52: 1364-1372, 2020.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu LSM11

Target: LSM11 (LSM11, U7 Small Nuclear RNA Associated (LSM11))

Andere Bezeichnung: LSM11

Hintergrund: LSM11 is a component of the U7 snRNP complex that is involved in the histone 3'-end pre-mRNA processing .Increases U7 snRNA levels but not histone 3'-end pre-mRNA processing activity, when overexpressed. Required for cellcycle progression from G1 to S phases.

Molekulargewicht: 68 kDa

Gen-ID: 134353

UniProt: P83369