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PUS7L Antikörper (AA 165-699)

PUS7L Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN7600226
  • Target Alle PUS7L Produkte
    PUS7L (Pseudouridylate Synthase 7 Homolog-Like (PUS7L))
    Bindungsspezifität
    • 2
    • 1
    • 1
    AA 165-699
    Reaktivität
    Human
    Wirt
    • 2
    • 2
    Kaninchen
    Klonalität
    • 4
    Polyklonal
    Konjugat
    • 4
    Dieser PUS7L Antikörper ist unkonjugiert
    Applikation
    Western Blotting (WB), ELISA
    Verwendungszweck
    Anti-PUS7L Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-PUS7L Antibody Picoband® (ABIN7600226). Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human PUS7L recombinant protein (Position: R165-H699).
    Isotyp
    IgG
  • Applikationshinweise
    Western blot, 0.25-0.5 μg/mL, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Jamieson, C.R., van der Burgt, I., Brady, A.F., van Reen, M., Elsawi, M.M., Hol, F., Jeffery, S., Patton, M.A. and Mariman, E. 1994. Mapping a gene for Noonan syndrome to the long arm of chromosome 12. Nat. Genet. 8: 357-360. 2. Yang, W. and Cole, W.G. 1998. Low basal transcripts of the COL2A1 collagen gene from lymphoblasts show alternative splicing of exon 12 in the Kniest form of spondyloepiphyseal dysplasia. Hum. Mutat. Suppl1: S1-S2. 3. Trowsdale, J., Barten, R., Haude, A., Stewart, C.A., Beck, S. and Wilson, M.J. 2001. The genomic context of natural killer receptor extended gene families. Immunol. Rev. 181: 20-38
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target
    PUS7L (Pseudouridylate Synthase 7 Homolog-Like (PUS7L))
    Andere Bezeichnung
    PUS7L (PUS7L Produkte)
    Hintergrund

    Synonyms: RNA-binding protein 47,RNA-binding motif protein 47,RBM47,

    Tissue Specificity: Abundantly expressed in tonsil, lymph node, and trachea, strong expression in prostate, lower expression in thyroid, stomach, and colon. .

    Background: Pseudouridylate synthase 7 homolog-like protein is an enzyme that in humans is encoded by the PUS7L gene. PUS7L (pseudouridylate synthase 7 homolog (S. cerevisiae) -like) is a 701 amino acid protein that belongs to the pseudouridine synthase truD family and contains one TRUD domain. The PUS7L gene is conserved in chimpanzee, canine, bovine, mouse, chicken and zebrafish, and maps to human chromosome 12q12. Encoding over 1,100 genes within 132 million bases, chromosome 12 makes up about 4.5 % of the human genome. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan syndrome, which includes heart and facial developmental defects among the primary symptoms, is caused by a mutant form of PTPN11 gene product, SH-PTP2. Chromosome 12 is also home to a homeobox gene cluster which encodes crucial transcription factors for morphogenesis, and the natural killer complex gene cluster encoding C-type lectin proteins which mediate the NK cell response to MHC I interaction.

    Molekulargewicht
    85 kDa
    Gen-ID
    83448
    UniProt
    Q9H0K6
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