BOP1 Antikörper (AA 157-701)

Produktnummer ABIN7600157

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BOP1 in WB, ELISA, IF, ICC und FACS. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für BOP1 Antikörper (AA 157-701) (ABIN7600157)

Target: BOP1 (Block of Proliferation 1 (BOP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BOP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Produktdetails anti-BOP1 Antikörper

Bindungsspezifität: AA 157-701

Verwendungszweck: Anti-BOP1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-BOP1 Antibody Picoband® (ABIN7600157). Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human BOP1 recombinant protein (Position: R157-N701). Human BOP1 shares 89.9% and 89.7% amino acid (aa) sequence identity with mouse and rat BOP1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL
1. Chen, B., Dragomir, M. P., Fabris, L., Bayraktar, R., Knutsen, E., Liu, X., Tang, C., Li, Y., Shimura, T., Ivkovic, T. C., Cruz de los Santos, M., Anfossi, S., and 36 others. The long noncoding RNA CCAT2 induces chromosomal instability through BOP1-AURKB signaling. Gastroenterology 159: 2146-2195, 2020. 2. Kellner, M., Rohrmoser, M., Forne, I., Voss, K., Burger, K., Muhl, B., Gruber-Eber, A., Kremmer, E., Imhof, A., Eick, D. DEAD-box helicase DDX27 regulates 3-prime end formation of ribosomal 47S RNA and stably associates with the PeBoW-complex. Exp. Cell Res. 334: 146-159, 2015. 3. Killian, A., Le Meur, N., Sesboue, R., Bourguignon, J., Bougeard, G., Gautherot, J., Bastard, C., Frebourg, T., Flaman, J.-M. Inactivation of the RRB1-pescadillo pathway involved in ribosome biogenesis induces chromosomal instability. Oncogene 23: 8597-8602, 2004.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu BOP1

Target: BOP1 (Block of Proliferation 1 (BOP1))

Andere Bezeichnung: BOP1

Hintergrund:

Synonyms: BOP1, KIAA0124, Ribosome biogenesis protein BOP1, Block of proliferation 1 protein

Background: Enables RNA binding activity. Involved in regulation of cell cycle, regulation of signal transduction by p53 class mediator, and ribosomal large subunit biogenesis. Located in chromosome, nucleolus, and nucleoplasm. Part of PeBoW complex.

Molekulargewicht: 110 kDa

Gen-ID: 23246

UniProt: Q14137