MINPP1 Antikörper (AA 155-421)

Produktnummer ABIN7600148

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MINPP1 in ELISA, WB, IHC und FACS. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für MINPP1 Antikörper (AA 155-421) (ABIN7600148)

Target: MINPP1 (Multiple Inositol-Polyphosphate Phosphatase 1 (MINPP1))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MINPP1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Produktdetails anti-MINPP1 Antikörper

Bindungsspezifität: AA 155-421

Verwendungszweck: Anti-MINPP1 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins

Produktmerkmale: Anti-MINPP1 Antibody Picoband® (ABIN7600148). Tested in WB, IHC, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human MINPP1 recombinant protein (Position: R155-H421). Human MINPP1 shares 89.5% and 89.9% amino acid (aa) sequence identity with mouse and rat MINPP1, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry, 2-5 μg/mL, Human, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL
1. Appelhof, B., Wagner, M., Hoefele, J., Heinze, A., Roser, T., Koch-Hogrebe, M., Roosendaal, S. D., Dehghani, M., Mehrjardi, M. Y. V., Torti, E., Houlden, H., Maroofian, R., Rajabi, F., Sticht, H., Baas, F., Wieczorek, D., Jamra, R. A. Pontocerebellar hypoplasia due to bi-allelic variants in MINPP1. Europ. J. Hum. Genet. 29: 411-421, 2021. 2. Caffrey, J. J., Hidaka, K., Matsuda, M., Hirata, M., Shears, S. B. The human and rat forms of multiple inositol polyphosphate phosphatase: functional homology with a histidine acid phosphatase up-regulated during endochondral ossification. FEBS Lett. 442: 99-104, 1999. 3. Chi, H., Tiller, G. E., Dasouki, M. J., Romano, P. R., Wang, J., O'Keefe, R. J., Puzas, J. E., Rosier, R. N., Reynolds, P. R. Multiple inositol polyphosphate phosphatase: evolution as a distinct group within the histidine phosphatase family and chromosomal localization of the human and mouse genes to chromosomes 10q23 and 19. Genomics 56: 324-336, 1999.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu MINPP1

Target: MINPP1 (Multiple Inositol-Polyphosphate Phosphatase 1 (MINPP1))

Andere Bezeichnung: MINPP1

Hintergrund:

Synonyms: MINPP1, MIPP, UNQ900/PRO1917, Multiple inositol polyphosphate phosphatase 1, EC 3.1.3.62, 2,3-bisphosphoglycerate 3-phosphatase, 2,3-BPG phosphatase, EC 3.1.3.80, Inositol, 1,3,4,5-tetrakisphosphate 3-phosphatase, Ins(1,3,4,5P(4 3-phosphatase

Background: his gene encodes multiple inositol polyphosphate phosphatase, an enzyme that removes 3-phosphate from inositol phosphate substrates. It is the only enzyme known to hydrolzye inositol pentakisphosphate and inositol hexakisphosphate. This enzyme also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate, an activity formerly thought to be exclusive to 2,3-BPG synthase/2-phosphatase (BPGM) in the Rapoport-Luebering shunt of the glycolytic pathway.

Molekulargewicht: 47 kDa

Gen-ID: 9562