GLMN Antikörper (AA 153-574)

Produktnummer ABIN7600137

Der Kaninchen Polyklonal Anti-GLMN-Antikörper wurde für WB, ELISA und FACS validiert. Er ist geeignet, GLMN in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für GLMN Antikörper (AA 153-574) (ABIN7600137)

Target: GLMN (Glomulin, FKBP Associated Protein (GLMN))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLMN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-GLMN Antikörper

Bindungsspezifität: AA 153-574

Verwendungszweck: Anti-GLMN Antibody Picoband®

Produktmerkmale: Anti-GLMN Antibody Picoband® (ABIN7600137). Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human GLMN recombinant protein (Position: Q153-R574). Human GLMN shares 85.4% amino acid (aa) sequence identity with mouse GLMN.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Arai, T., Kasper, J. S., Skaar, J. R., Ali, S. H., Takahashi, C., DeCaprio, J. A. Targeted disruption of p185/Cul7 gene results in abnormal vascular morphogenesis. Proc. Nat. Acad. Sci. 100: 9855-9860, 2003. 2. Brouillard, P., Boon, L. M., Mulliken, J. B., Enjolras, O., Ghassibe, M., Warman, M. L., Tan, O. T., Olsen, B. R., Vikkula, M. Mutations in a novel factor, glomulin, are responsible for glomuvenous malformations ('glomangiomas'). Am. J. Hum. Genet. 70: 866-874, 2002. 3. Brouillard, P., Olsen, B. R., Vikkula, M. High-resolution physical and transcript map of the locus for venous malformations with glomus cells (VMGLOM) on chromosome 1p21-p22. Genomics 67: 96-101, 2000.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu GLMN

Target: GLMN (Glomulin, FKBP Associated Protein (GLMN))

Andere Bezeichnung: GLMN

Hintergrund: Glomulin is a protein that in humans is encoded by the GLMN gene. This gene encodes a phosphorylated protein that is a member of a Skp1-Cullin-F-box-like complex. The protein is essential for normal development of the vasculature and mutations in this gene have been associated with glomuvenous malformations, also called glomangiomas. Multiple splice variants encoding different isoforms have been found for this gene.

Molekulargewicht: 68 kDa

Gen-ID: 11146

UniProt: Q92990

Pathways: Tube Formation