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TSEN54 Antikörper (AA 147-507)

Dieses Anti-TSEN54-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TSEN54 in WB, IHC, ELISA, ICC, IF und FACS. Geeignet für Human.
Produktnummer ABIN7600084

Kurzübersicht für TSEN54 Antikörper (AA 147-507) (ABIN7600084)

Target

Alle TSEN54 Antikörper anzeigen
TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))

Reaktivität

  • 14
  • 9
  • 1
Human

Wirt

  • 13
  • 1
Kaninchen

Klonalität

  • 14
Polyklonal

Konjugat

  • 7
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser TSEN54 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)
  • Bindungsspezifität

    • 2
    • 1
    • 1
    • 1
    • 1
    AA 147-507

    Verwendungszweck

    Anti-TSEN54 Antibody Picoband®

    Kreuzreaktivität (Details)

    No cross-reactivity with other proteins.

    Produktmerkmale

    Anti-TSEN54 Antibody Picoband® (ABIN7600084). Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Aufreinigung

    Immunogen affinity purified.

    Immunogen

    E.coli-derived human TSEN54 recombinant protein (Position: D147-H507).

    Isotyp

    IgG
  • Applikationshinweise

    Western blot, 0.1-0.25 μg/mL, Human
    Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
    Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
    ELISA, 0.1-0.5 μg/mL, -
    1. Barth, P. G., Aronica, E., de Vries, L., Nikkels, P. G. J., Scheper, W., Hoozemans, J. J., Poll-The, B.-T., Troost, D. Pontocerebellar hypoplasia type 2: a neuropathological update. Acta Neuropath. 114: 373-386, 2007. 2. Budde, B. S., Namavar, Y., Barth, P. G., Poll-The, B. T., Nurnberg, G., Becker, C., van Ruissen, F., Weterman, M. A. J., Fluiter, K., te Beek, E. T., Aronica, E., van der Knaap, M. S., and 26 others. tRNA splicing endonuclease mutations cause pontocerebellar hypoplasia. Nature Genet. 40: 1113-1118, 2008. 3. Cassandrini, D., Biancheri, R., Tessa, A., Di Rocco, M., Di Capua, M., Bruno, C., Denora, P. S., Sartori, S., Rossi, A., Nozza, P., Emma, F., Mezzano, P., Politi, M. R., Laverda, A. M., Zara, F., Pavone, L., Simonati, A., Leuzzi, V., Santorelli, F. M., Bertini, E. Pontocerebellar hypoplasia: clinical, pathologic, and genetic studies. Neurology 75: 1459-1464, 2010.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Konzentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.
  • Target

    TSEN54 (tRNA Splicing Endonuclease 54 (TSEN54))

    Andere Bezeichnung

    TSEN54

    Hintergrund

    Synonyms: Forkhead box protein F1, Forkhead-related activator 1, FREAC-1, Forkhead-related protein FKHL5, Forkhead-related transcription factor 1, FOXF1, FKHL5, FREAC1

    Tissue Specificity: Expressed in kidney.

    Background: This gene encodes a subunit of the tRNA splicing endonuclease complex, which catalyzes the removal of introns from precursor tRNAs. The complex is also implicated in pre-mRNA 3-prime end processing. Mutations in this gene result in pontocerebellar hypoplasia type 2.

    Molekulargewicht

    59 kDa

    Gen-ID

    283989

    UniProt

    Q7Z6J9

    Pathways

    Synaptic Membrane
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