NADK2 Antikörper (AA 145-442)

Produktnummer ABIN7600068

Der Kaninchen Polyklonal Anti-NADK2-Antikörper wurde für WB, ELISA, FACS, ICC und IF validiert. Er ist geeignet, NADK2 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für NADK2 Antikörper (AA 145-442) (ABIN7600068)

Target: NADK2 (NAD Kinase 2, Mitochondrial (NADK2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NADK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)

Produktdetails anti-NADK2 Antikörper

Bindungsspezifität: AA 145-442

Verwendungszweck: Anti-C5orf33/NADK2 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-C5orf33/NADK2 Antibody Picoband® (ABIN7600068). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human C5orf33/NADK2 recombinant protein (Position: D145-Q442).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Hartz, P. A. Personal Communication. Baltimore, Md. 5/12/2014. 2. Houten, S. M., Denis, S., te Brinke, H., Jongejan, A., van Kampen, A. H. C., Bradley, E. J., Baas, F., Hennekam, R. C. M., Millington, D. S., Young, S. P., Frazier, D. M., Gucsavas-Calikoglu, M., Wanders, R. J. A. Mitochondrial NADP(H) deficiency due to a mutation in NADK2 causes dienoyl-CoA reductase deficiency with hyperlysinemia. Hum. Molec. Genet. 23: 5009-5016, 2014. 3. Ohashi, K., Kawai, S., Murata, K. Identification and characterization of a human mitochondrial NAD kinase. Nature Commun. 3: 1248, 2012. Note: Electronic Article.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu NADK2

Target: NADK2 (NAD Kinase 2, Mitochondrial (NADK2))

Andere Bezeichnung: NADK2

Hintergrund:

Synonyms: Peflin, PEF protein with a long N-terminal hydrophobic domain, Penta-EF hand domain-containing protein 1, PEF1, ABP32, UNQ1845, PRO3573

Tissue Specificity: Pre-B-cells and B-cells but not terminally differentiated plasma cells.

Background: This gene encodes a mitochondrial kinase that catalyzes the phosphorylation of NAD to yield NADP. Mutations in this gene result in 2,4-dienoyl-CoA reductase deficiency. Alternative splicing results in multiple transcript variants.

Molekulargewicht: 53 kDa

Gen-ID: 133686

UniProt: Q4G0N4