PNPLA1 Antikörper (AA 141-496)

Produktnummer ABIN7600045

Dieses Anti-PNPLA1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PNPLA1 in ELISA und WB. Geeignet für Human.

Kurzübersicht für PNPLA1 Antikörper (AA 141-496) (ABIN7600045)

Target: PNPLA1 (Patatin-Like phospholipase Domain Containing 1 (PNPLA1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PNPLA1 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-PNPLA1 Antikörper

Bindungsspezifität: AA 141-496

Verwendungszweck: Anti-PNPLA1 Antibody Picoband®

Produktmerkmale: Anti-PNPLA1 Antibody Picoband® (ABIN7600045). Tested in WB, ELISA applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PNPLA1 recombinant protein (Position: K141-D496). Human PNPLA1 shares 51.5% amino acid (aa) sequence identity with mouse PNPLA1.

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -
1. Ahmad, F., Ansar, M., Mehmood, S., Izoduwa, A., Lee, K., Nasir, A., Abrar, M., Mehmood, S., Ullah, A., Aziz, A., University of Washington Center for Mendelian Genomics, Smith, J. D., Shendure, J., Bamshad, M. J., Nicekrson, D. A., Santos-Cortez, R. L. P., Leal, S. M., Ahmad, W. A novel missense variant in the PNPLA1 gene underlies congenital ichthyosis in three consanguineous families. J. Europ. Acad. Derm. Venereol. 30: e210-e213, 2016. Note: Electronic Article. 2. Boyden, L. M., Craiglow, B. G., Hu, R. H., Zhou, J., Browning, J., Eishenfield, L., Lim, Y. L., Luu, M., Randolph, L. M., Ginarte, M., Fachal, L., Rodriguez-Pazos, L., and 10 others. Phenotypic spectrum of autosomal recessive congenital ichthyosis due to PNPLA1 mutation. Brit. J. Derm. 177: 319-322, 2017. 3. Fachal, L., Rodriguez-Pazos, L., Ginarte, M., Carracedo, A., Toribio, J., Vega, A. Identification of a novel PNPLA1 mutation in a Spanish family with autosomal recessive congenital ichthyosis. (Letter) Brit. J. Derm. 170: 980-982, 2014.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu PNPLA1

Target: PNPLA1 (Patatin-Like phospholipase Domain Containing 1 (PNPLA1))

Andere Bezeichnung: PNPLA1

Hintergrund: PNPLA1 is important in the formation of the epidermal lipid barrier and plays a role in glycerophospholipid metabolism.

Molekulargewicht: 58 kDa

Gen-ID: 285848

UniProt: Q8N8W4