SMC5 Antikörper (AA 14-1089)

Produktnummer ABIN7600007

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SMC5 in WB, ELISA, IF, ICC und FACS. Er zeigt eine Reaktivität gegenüber Human, Ratte und Maus.

Kurzübersicht für SMC5 Antikörper (AA 14-1089) (ABIN7600007)

Target: SMC5 (Structural Maintenance of Chromosomes 5 (SMC5))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMC5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Produktdetails anti-SMC5 Antikörper

Bindungsspezifität: AA 14-1089

Verwendungszweck: Anti-SMC5 Antibody Picoband®

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-SMC5 Antibody Picoband® (ABIN7600007). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human SMC5 recombinant protein (Position: Q14-Q1089).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Decorsiere, A., Mueller, H., van Breugel, P. C., Abdul, F., Gerossier, L., Beran, R. K., Livingston, C. M., Niu, C., Fletcher, S. P., Hantz, O., Strubin, M. Hepatitis B virus X protein identifies the Smc5/6 complex as a host restriction factor. Nature 531: 386-389, 2016. 2. Kuniba, H., Yoshiura, K., Kondoh, T., Ohashi, H., Kurosawa, K., Tonoki, H., Nagai, T., Okamoto, N., Kato, M., Fukushima, Y., Kaname, T., Naritomi, K., Matsumoto, T., Moriuchi, H., Kishino, T., Kinoshita, A., Miyake, N., Matsumoto, N., Niikawa, N. Molecular karyotyping in 17 patients and mutation screening in 41 patients with Kabuki syndrome. J. Hum. Genet. 54: 304-309, 2009. 3. Nagase, T., Ishikawa, K., Miyajima, N., Tanaka, A., Kotani, H., Nomura, N., Ohara, O. Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro. DNA Res. 5: 31-39, 1998.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Details zu SMC5

Target: SMC5 (Structural Maintenance of Chromosomes 5 (SMC5))

Andere Bezeichnung: SMC5

Hintergrund:

Synonyms: Hepatic leukemia factor, HLF

Tissue Specificity: Highly expressed in liver, lower levels in lung and kidney.

Background: Structural maintenance of chromosomes protein 5 is a protein encoded by the SMC5 gene in human. Predicted to enable ATP binding activity. Involved in several processes, including DNA recombination, cellular senescence, and positive regulation of maintenance of mitotic sister chromatid cohesion. Located in cell junction, chromosome, and nuclear body. Part of Smc5-Smc6 complex.

Molekulargewicht: 130 kDa

Gen-ID: 23137